Title:
ANTICONVULSANT DERIVATIVES USEFUL IN TREATING CHRONIC NEURODEGENERATIVE DISORDERS
Document Type and Number:
WIPO Patent Application WO2000061138
Kind Code:
A8
Abstract:
Use of anticonvulsant derivatives of formula (I) for treating chronic neurodegenerative conditions, wherein X is CH2 or oxygen; R1 is hydrogen or C1-C4 alkyl; and R2, R3, R4 and R5 are independently hydrogen or alkyl and, when X is CH2, R4 and R5 may be alkene groups joined to form a benzene ring and, when X is oxygen, R2 and R3 and/or R4 and R5 together may be a methylenedioxy group of formula (II), wherein R6 and R7 are the same or different and are hydrogen, or alkyl and are joined to form a cyclopentyl or cyclohexyl ring.
Inventors:
SHANK RICHARD P
SMITH-SWINTOSKY GINGER
ZHAO BOYU
SMITH-SWINTOSKY GINGER
ZHAO BOYU
Application Number:
PCT/US2000/008401
Publication Date:
January 10, 2002
Filing Date:
March 30, 2000
Export Citation:
Assignee:
ORTHO MCNEIL PHARM INC (US)
International Classes:
A61K31/255; A61K31/35; A61K31/357; A61K31/7048; A61P3/10; C07D493/14; A61P9/10; A61P25/00; A61P25/02; A61P25/08; A61P25/14; A61P25/16; A61P25/28; (IPC1-7): A61K31/255; A61K31/35; A61K31/7048; A61P25/00; A61P25/28
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