Title:
ANTIGEN STIMULANT FOR DETECTING MYCOBACTERIUM TUBERCULOSIS INFECTION, KIT, AND APPLICATIONS OF ANTIGEN STIMULANT
Document Type and Number:
WIPO Patent Application WO/2016/095273
Kind Code:
A1
Abstract:
Disclosed are an antigen stimulant for detecting mycobacterium tuberculosis infection, and a kit comprising the antigen stimulant. Further disclosed are applications of the antigen stimulant in reagents for detecting mycobacterium tuberculosis infection. The antigen stimulant comprises at least one polypeptide or analogues thereof of polypeptides shown by sequences 1 to 11 in a sequence table, wherein the polypeptides respectively come from tuberculosis specific antigen polypeptides ESAT-6 and tuberculosis specific antigen polypeptides CFP-10. The disclosed antigen stimulant can stimulate peripheral blood T lymphocytes of a tuberculosis infection patient to generate IFN-γ to diagnose the tuberculosis infection, and is not affected by BCG inoculation or other underlying diseases.
Inventors:
ZENG GUCHENG (CN)
WANG HUA (CN)
WANG HUA (CN)
Application Number:
PCT/CN2014/095543
Publication Date:
June 23, 2016
Filing Date:
December 30, 2014
Export Citation:
Assignee:
GUANGZHOU YIDAI PHARMACEUTICAL CO LTD (CN)
International Classes:
G01N33/564; C12Q1/68
Domestic Patent References:
| WO2004005925A2 | 2004-01-15 |
Foreign References:
| CN101493454A | 2009-07-29 | |||
| CN102187224A | 2011-09-14 | |||
| CN101419237A | 2009-04-29 | |||
| CN103604933A | 2014-02-26 |
Attorney, Agent or Firm:
GUANGZHOU SINO PATENT & TRADEMARK AGENT CO., LTD. (CN)
广州新诺专利商标事务所有限公司 (CN)
广州新诺专利商标事务所有限公司 (CN)
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