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Title:
ANTIPRURITIC AGENT
Document Type and Number:
WIPO Patent Application WO/1998/023290
Kind Code:
A1
Abstract:
An antipruritic agent comprising as the active ingredient an opioid $g(k) receptor agonist useful for the treatment of pruritus in various diseases accompanied by pruritus, and novel morphinane quaternary ammonium salt derivatives and morphinane N-oxide derivatives.

Inventors:
NAGASE HIROSHI (JP)
UTSUMI JUN (JP)
ENDOH TAKASHI (JP)
TANAKA TOSHIAKI (JP)
KAMEI JUNZO (JP)
KAWAMURA KUNIAKI (JP)
Application Number:
PCT/JP1997/004267
Publication Date:
June 04, 1998
Filing Date:
November 21, 1997
Export Citation:
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Assignee:
TORAY INDUSTRIES (JP)
NAGASE HIROSHI (JP)
UTSUMI JUN (JP)
ENDOH TAKASHI (JP)
TANAKA TOSHIAKI (JP)
KAMEI JUNZO (JP)
KAWAMURA KUNIAKI (JP)
International Classes:
A61K31/40; A61K31/4025; A61K31/435; A61K31/485; A61K31/5377; A61K31/541; A61P17/04; C07D489/00; C07D489/08; (IPC1-7): A61K45/00; A61K31/40; A61K31/54; C07D279/12; C07D295/14; C07D491/08
Domestic Patent References:
WO1995021843A11995-08-17
Other References:
See also references of EP 0897726A4
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