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Title:
ANTIPRURITICS
Document Type and Number:
WIPO Patent Application WO/2003/070277
Kind Code:
A1
Abstract:
It is intended to provide antipruritics (drugs to control itching, antiitch agents and drugs to stop itching). It is found out that a compound having a cannabinoid receptor agonism shows an antipruritic effect.

Inventors:
YASUI KIYOSHI (JP)
MORIOKA YASUHIDE (JP)
HANASAKI KOHJI (JP)
Application Number:
PCT/JP2003/001725
Publication Date:
August 28, 2003
Filing Date:
February 18, 2003
Export Citation:
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Assignee:
SHIONOGI & CO (JP)
YASUI KIYOSHI (JP)
MORIOKA YASUHIDE (JP)
HANASAKI KOHJI (JP)
International Classes:
A61K31/00; A61K31/426; A61K31/435; A61K31/436; A61K31/4375; A61K31/4412; A61K31/4439; A61K31/4523; A61K31/4704; A61K31/4709; A61K31/4745; A61K31/506; A61K31/5377; A61K31/54; A61K31/541; A61K31/5415; A61K31/547; A61P17/04; C07D213/69; C07D213/70; C07D213/75; C07D213/82; C07D215/38; C07D215/54; C07D217/26; C07D221/04; C07D221/12; C07D221/22; C07D263/46; C07D277/18; C07D279/06; C07D279/08; C07D401/04; C07D401/06; C07D401/12; C07D403/06; C07D405/12; C07D405/14; C07D411/12; C07D413/12; C07D413/14; C07D417/04; C07D417/06; C07D417/12; C07D455/06; C07D471/04; C07D493/04; C07D513/04; C07D513/10; (IPC1-7): A61K45/00; A61K31/426; A61K31/435; A61K31/436; A61K31/4375; A61K31/4412; A61K31/4427; A61K31/4439; A61K31/4523; A61K31/4704; A61K31/4709; A61K31/4745; A61K31/506; A61K31/5377; A61K31/54; A61K31/541; A61K31/5415; A61K31/547; A61P17/04
Domestic Patent References:
WO2002053543A12002-07-11
WO2001019807A12001-03-22
Foreign References:
US20020182159A12002-12-05
JPH11500411A1999-01-12
JPH05345722A1993-12-27
Other References:
DARMANI N.A. ET AL.: "Cannabinoids of diverse structure inhibit two DOI-induced 5-HT2A receptor-mediated behaviors in mice", PHARMACOLOGY, BIOCHEMISTRY AND BEHAVIOR, vol. 68, no. 2, 2001, pages 311 - 317, XP002952871
BUEB JEAN-LUC ET AL.: "Receptor-independent effects of natural cannabinoids in rat peritoneal mast cells in vitro", BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1538, no. 2-3, 2001, pages 252 - 259, XP004235740
Attorney, Agent or Firm:
Yamauchi, Hideaki (Intellectual Property Department, 12-4, Sagisu 5-chome, Fukushima-k, Osaka-shi Osaka, JP)
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