Title:
ANTISENSE MODULATION OF SUPEROXIDE DISMUTASE 1, SOLUBLE EXPRESSION
Document Type and Number:
WIPO Patent Application WO2003000707
Kind Code:
A9
Abstract:
Antisense compounds, compositions and methods are provided for modulating the expression of superoxide dismutase 1, soluble. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding superoxide dismutase 1, soluble. Methods of using these compounds for modulation of superoxyde dismutase 1, soluble expression and for treatment of diseases associated with expression of superoxide dismutase 1, soluble are provided.
Inventors:
BENNETT C FRANK (US)
DOBIE KENNETH (US)
DOBIE KENNETH (US)
Application Number:
PCT/US2002/019664
Publication Date:
January 30, 2003
Filing Date:
June 19, 2002
Export Citation:
Assignee:
ISIS PHARMACEUTICALS INC (US)
BENNETT C FRANK (US)
DOBIE KENNETH (US)
BENNETT C FRANK (US)
DOBIE KENNETH (US)
International Classes:
C12N15/113; A61K38/00; (IPC1-7): C07H/
Download PDF:
Previous Patent: METALLOCENES, USE IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS
Next Patent: SIALIC ACID DERIVATIVES FOR USE AS SIGLEC INHIBITORS
Next Patent: SIALIC ACID DERIVATIVES FOR USE AS SIGLEC INHIBITORS