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Title:
ANTISENSE OLIGONUCLEOTIDES FOR TREATMENT OF CANCER STEM CELLS
Document Type and Number:
WIPO Patent Application WO/2014/153209
Kind Code:
A8
Abstract:
The invention provides oligonucleotides complementary to a non-coding chimeric mitochondrial RNA as well as compositions and kits comprising the same, and their use in treating and preventing metastasis or relapse of a cancer in an individual previously treated for cancer with a therapy. The invention also provides oligonucleotides complementary to a non-coding chimeric mitochondrial RNA as well as compositions and kits comprising the same, and their use in treating a refractory cancer (e.g., a refractory HPV-associated cancer).

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Inventors:
BURZIO ERIZ LUIS O (CL)
BURZIO MENENDEZ VERONICA A (CL)
VILLEGAS OLAVARRIA JAIME E (CL)
Application Number:
PCT/US2014/029606
Publication Date:
February 26, 2015
Filing Date:
March 14, 2014
Export Citation:
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Assignee:
ANDES BIOTECHNOLOGIES S A (CL)
MONROY GLADYS (US)
International Classes:
C12N15/11; A61K48/00; C12N5/00; C12N15/00
Attorney, Agent or Firm:
SHOW, Matthew D. et al. (755 Page Mill RoadPalo Alto, CA, US)
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