ANTITUMOR AGENT POTENTIATOR COMPRISING IL-6 ANTAGONIST

Title:

ANTITUMOR AGENT POTENTIATOR COMPRISING IL-6 ANTAGONIST

Document Type and Number:

WIPO Patent Application WO/1996/020728

Kind Code:

A1

Abstract:

A potentiator for antitumor agents, for example, platinum compounds such as cisplatin and carboplatin, mitomycin C, etc., which comprises an interleukin-6 (IL-6) antagonist such as an antibody against IL-6, an antibody against IL-6 receptor, an antibody against protein gp130, etc.

Inventors:

YOSHIDA OSAMU (JP)
MIZUTANI YOUICHI (JP)

Application Number:

PCT/JP1995/002769

Publication Date:

July 11, 1996

Filing Date:

December 28, 1995

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Assignee:

CHUGAI PHARMACEUTICAL CO LTD (JP)
YOSHIDA OSAMU (JP)
MIZUTANI YOUICHI (JP)

International Classes:

A61K31/28; A61K31/282; A61K38/00; A61K33/243; A61K39/395; A61K45/00; A61K45/06; A61P35/00; A61P43/00; C12P21/08; (IPC1-7): A61K45/00

Other References:

VINK, A JOURNAL OF EXPERIMENTAL MEDICINE, September 1990, Vol. 172, No. 3, pages 997-1000.

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