APO AI EXPRESSION ACCELERATING AGENT

Title:

APO AI EXPRESSION ACCELERATING AGENT

Document Type and Number:

WIPO Patent Application WO/2003/018008

Kind Code:

A1

Abstract:

A medicinal composition having apo AI expression accelerating action, which comprises a compound represented by the formula (I): (I) wherein Y¹ represents O, S or NR¹, Y², Y³, Y⁴and Y⁵ represent CR²or N, CR³or N, CR⁴or N, and CR⁵or N, respectively, R¹ represents A¹, −Z−A², hydrogen, a lower alkyl or the like, R², R³, R⁴and R⁵ represent A¹, −Z−A², hydrogen, a halogen or the like, −Z− represents a single bond, −CR⁶=CR⁷− or the like, R⁶ and R⁷ are hydrogen or a lower alkyl, and A¹and A² are an aryl, a heterocyclic group or the like, or the like.

Inventors:

ISHIZUKA NATSUKI (JP)
NAGATA KIYOSHI (JP)
YAMAMORI TERUO (JP)
SAKAI KATSUNORI (JP)

Application Number:

PCT/JP2001/007238

Publication Date:

March 06, 2003

Filing Date:

August 24, 2001

Export Citation:

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Assignee:

SHIONOGI & CO (JP)
ISHIZUKA NATSUKI (JP)
NAGATA KIYOSHI (JP)
YAMAMORI TERUO (JP)
SAKAI KATSUNORI (JP)

International Classes:

A61K31/341; A61K31/351; A61K31/381; A61K31/40; A61K31/4025; A61K31/41; A61K31/415; A61K31/4155; A61K31/4164; A61K31/4178; A61K31/4192; A61K31/42; A61K31/421; A61K31/422; A61K31/4245; A61K31/425; A61K31/426; A61K31/427; A61K31/433; A61K31/4427; A61K31/443; A61K31/4433; A61K31/4436; A61K31/4439; A61K31/454; A61K31/496; A61K31/501; A61K31/506; A61K31/5375; A61K31/5377; A61P3/06; A61P9/10; A61P43/00; C07D207/32; C07D207/34; C07D207/50; C07D231/12; C07D231/14; C07D233/56; C07D249/08; C07D249/10; C07D249/12; C07D257/04; C07D261/08; C07D263/32; C07D271/06; C07D271/10; C07D271/107; C07D277/22; C07D277/24; C07D285/06; C07D285/08; C07D285/10; C07D285/12; C07D285/135; C07D307/36; C07D307/38; C07D307/42; C07D307/68; C07D333/06; C07D333/12; C07D333/16; C07D333/18; C07D401/04; C07D401/14; C07D403/04; C07D405/04; C07D405/14; C07D407/04; C07D409/04; C07D409/14; C07D413/04; C07D413/06; C07D413/14; C07D417/04; C07D417/10; C07D249/06; C07D417/14; (IPC1-7): A61K31/415; A61K31/427; A61K31/42; A61K31/421; A61K31/454; A61K31/506; A61K31/40; A61K31/4025; A61K31/381; A61K31/4436; A61K31/426; A61K31/41; A61K31/433; A61K31/422; A61K31/4439; A61K31/501; A61K31/5377; A61K31/351; A61K31/4164; A61K31/4178; A61K31/425; A61P43/00; A61P3/06; A61P9/10

Domestic Patent References:

WO2000015213A1	2000-03-23
WO2001056993A2	2001-08-09
WO2001046172A1	2001-06-28

Foreign References:

JP2001233767A	2001-08-28
JP2001131151A	2001-05-15
US4829081A	1989-05-09
US4829081A	1989-05-09
JP2001131151A	2001-05-15

Other References: