Title:
APPARATUS FOR AND METHOD OF MEASURING INTRACRANIAL DYNAMICS
Document Type and Number:
WIPO Patent Application WO/2022/180306
Kind Code:
A3
Abstract:
An apparatus for measuring intracranial dynamics comprises the at least one sensing device (100): an electroencephalographic electrode arrangement, which senses direct-current electroencephalographic signals from the brain, an optic measurement arrangement (120), which directs optic radiation toward the brain through the cranium, and receives the optic radiation reflected and/or scattered therefrom, and/or a capacitive sensor arrangement (130), which senses electric potential signals of the head. The apparatus additionally comprises a data processing arrangement (150), which receives electric signals from the at least one sensing device (100), and determine data on at least one of the following dynamics: glymphatic activity, water within the cranium, brain tissue movements, water and/or electrolyte movements and intracranial pressure based on said electric signals from the at least one sensing device (100). The data processing arrangement (150) then outputs at least one piece of the data on the dynamics through a user interface (152).
Inventors:
MYLLYLÄ TEEMU (FI)
KIVINIEMI VESA (FI)
KIVINIEMI VESA (FI)
Application Number:
PCT/FI2022/050119
Publication Date:
October 06, 2022
Filing Date:
February 23, 2022
Export Citation:
Assignee:
OULUN YLIOPISTO (FI)
International Classes:
A61B5/00; A61B5/24; A61B5/37; A61B5/03; A61B5/0537
Other References:
KIVINIEMI VESA ET AL: "Real-time monitoring of human blood-brain barrier disruption", PLOS ONE, vol. 12, no. 3, 20 March 2017 (2017-03-20), pages 1 - 16, XP055950675, Retrieved from the Internet DOI: 10.1371/journal.pone.0174072
MYLLYLÄ TEEMU ET AL: "Functional NIRS study of blood brain barrier disruption when induced by focused ultrasound and intra-arterial mannitol infusion", SPIE PROCEEDINGS; [PROCEEDINGS OF SPIE ISSN 0277-786X], SPIE, US, vol. 11363, 5 May 2020 (2020-05-05), pages 1 - 6, XP060132043, ISBN: 978-1-5106-3673-6, DOI: 10.1117/12.2555843
MYLLYLÄ TEEMU ET AL: "Assessment of the dynamics of human glymphatic system by near-infrared spectroscopy", JOURNAL OF BIOPHOTONICS, vol. 11, no. 8, 19 December 2017 (2017-12-19), DE, pages 1 - 9, XP055950684, ISSN: 1864-063X, Retrieved from the Internet DOI: 10.1002/jbio.201700123
MYLLYLÄ TEEMU ET AL: "Prototype of an opto-capacitive probe for non-invasive sensing cerebrospinal fluid circulation", PROGRESS IN BIOMEDICAL OPTICS AND IMAGING, SPIE - INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, BELLINGHAM, WA, US, vol. 10063, 3 March 2017 (2017-03-03), pages 1 - 7, XP060084675, ISSN: 1605-7422, ISBN: 978-1-5106-0027-0, DOI: 10.1117/12.2251977
MYLLYLÄ TEEMU ET AL: "Functional NIRS study of blood brain barrier disruption when induced by focused ultrasound and intra-arterial mannitol infusion", SPIE PROCEEDINGS; [PROCEEDINGS OF SPIE ISSN 0277-786X], SPIE, US, vol. 11363, 5 May 2020 (2020-05-05), pages 1 - 6, XP060132043, ISBN: 978-1-5106-3673-6, DOI: 10.1117/12.2555843
MYLLYLÄ TEEMU ET AL: "Assessment of the dynamics of human glymphatic system by near-infrared spectroscopy", JOURNAL OF BIOPHOTONICS, vol. 11, no. 8, 19 December 2017 (2017-12-19), DE, pages 1 - 9, XP055950684, ISSN: 1864-063X, Retrieved from the Internet
MYLLYLÄ TEEMU ET AL: "Prototype of an opto-capacitive probe for non-invasive sensing cerebrospinal fluid circulation", PROGRESS IN BIOMEDICAL OPTICS AND IMAGING, SPIE - INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, BELLINGHAM, WA, US, vol. 10063, 3 March 2017 (2017-03-03), pages 1 - 7, XP060084675, ISSN: 1605-7422, ISBN: 978-1-5106-0027-0, DOI: 10.1117/12.2251977
Attorney, Agent or Firm:
KOLSTER OY AB (FI)
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