Title:
APPARATUS AND METHOD FOR PRODUCING HYDROXYAPATITE CONTAINING ANTIBACTERIAL METAL
Document Type and Number:
WIPO Patent Application WO/2023/209788
Kind Code:
A1
Abstract:
In the present embodiment, the production apparatus is provided with a first injection device, a second injection device, a control device, and a pouring device. The first injection device injects calcium hydroxide into a container. The second injection device injects a mixed solution prepared by mixing silver nitrate, copper nitrate or copper sulfate with phosphoric acid into the solution stored in the container. The control unit controls at least one of the concentration and the injection speed of the mixed solution to be injected by the second injection device in such a manner that the pH value measured by a pH meter falls within a predetermined range, thereby producing a light-gray or white hydroxyapatite suspension containing an antibacterial metal in the container.
Inventors:
TANAKA NOBUKIYO (JP)
TANAKA MASASHI (JP)
TANAKA MASASHI (JP)
Application Number:
PCT/JP2022/018811
Publication Date:
November 02, 2023
Filing Date:
April 26, 2022
Export Citation:
Assignee:
BRAINY INC (JP)
International Classes:
A61L31/02; A01N59/26; A61K6/75; A61K8/24; A61L15/18; C01B25/45
Foreign References:
| JP2019528364A | 2019-10-10 | |||
| JPH02180270A | 1990-07-13 | |||
| JPH06200238A | 1994-07-19 | |||
| JP2010273847A | 2010-12-09 | |||
| JPS62252307A | 1987-11-04 | |||
| JP2019155209A | 2019-09-19 | |||
| JP2007075595A | 2007-03-29 |
Other References:
MOHD PU'AD N.A.S., ABDUL HAQ R.H., MOHD NOH H., ABDULLAH H.Z., IDRIS M.I., LEE T.C.: "Synthesis method of hydroxyapatite: A review", MATERIALS TODAY: PROCEEDINGS, ELSEVIER, NL, vol. 29, 1 January 2020 (2020-01-01), NL , pages 233 - 239, XP093104604, ISSN: 2214-7853, DOI: 10.1016/j.matpr.2020.05.536
GOITSUKA, YUKARI: "Experiments Forum. Silver reactions. ", CHEMICAL EDUCATION, NIPPON KAGAKKAI, JP, vol. 66, no. 12, 1 December 2018 (2018-12-01), JP , pages 580 - 581, XP009550500, ISSN: 0386-2151
AL-ESSA KHANSAA, RADHA A V, NAVROTSKY ALEXANDRA: "Drop Solution Calorimetric Studies of Interface Enthalpy of Cubic Silver (I) Oxide (Ag2O) Nanocrystals", KEY ENGINEERING MATERIALS, vol. 878, pages 73 - 80, XP093104608, DOI: 10.4028/www.scientific.net/KEM.878.73
GOITSUKA, YUKARI: "Experiments Forum. Silver reactions. ", CHEMICAL EDUCATION, NIPPON KAGAKKAI, JP, vol. 66, no. 12, 1 December 2018 (2018-12-01), JP , pages 580 - 581, XP009550500, ISSN: 0386-2151
AL-ESSA KHANSAA, RADHA A V, NAVROTSKY ALEXANDRA: "Drop Solution Calorimetric Studies of Interface Enthalpy of Cubic Silver (I) Oxide (Ag2O) Nanocrystals", KEY ENGINEERING MATERIALS, vol. 878, pages 73 - 80, XP093104608, DOI: 10.4028/www.scientific.net/KEM.878.73
Attorney, Agent or Firm:
S & S INTERNATIONAL PPC (JP)
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