Title:
APPARATUS AND METHOD FOR PROPOSING OPTIMAL BIOMARKER ANALYSIS METHOD BASED ON MULTI-INFORMATION ANALYSIS
Document Type and Number:
WIPO Patent Application WO/2024/025136
Kind Code:
A1
Abstract:
The present disclosure relates to a method and apparatus for proposing an optimal biomarker analysis method based on multi-information analysis. The present method may comprise the steps of: receiving digital image information about a tissue embedded in paraffin and storage information about the tissue; calculating, on the basis of the digital image information and the storage information, the amount of paraffin sections that can be extracted from the tissue; calculating the amount of nucleic acids required for each of a plurality of tests; determining, on the basis of the calculated amount of paraffin sections and the calculated amount of nucleic acids, whether at least one of the plurality of tests is successful; and selecting, on the basis of a determination result of each of the plurality of tests, an optimal test from among the plurality of tests for the tissue.
Inventors:
KIM TAE JUNG (KR)
Application Number:
PCT/KR2023/007905
Publication Date:
February 01, 2024
Filing Date:
June 09, 2023
Export Citation:
Assignee:
CATHOLIC UNIV KOREA IND ACADEMIC COOPERATION FOUNDATION (KR)
International Classes:
G16B40/20; G06N3/08; G06N20/00; G16B5/00; G16B35/00
Domestic Patent References:
| WO2022147503A1 | 2022-07-07 | |||
| WO2018065434A1 | 2018-04-12 |
Foreign References:
| KR20210017294A | 2021-02-17 |
Other References:
HE CHANGLONG; WEI CHENGCHENG; WEN JUN; CHEN SHI; CHEN LING; WU YUE; SHEN YIFAN; BAI HUILI; ZHANG YANGLI; CHEN XUEPING; LI XIAOSONG: "Comprehensive analysis of NGS and ARMS-PCR for detecting EGFR mutations based on 4467 cases of NSCLC patients", JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, SPRINGER INTERNATIONAL, BERLIN., DE, vol. 148, no. 2, 24 October 2021 (2021-10-24), DE , pages 321 - 330, XP037679137, ISSN: 0171-5216, DOI: 10.1007/s00432-021-03818-w
OSINSKI BOLESŁAW L, BENTAIEB AÏCHA, HO IRVIN, JONES RYAN D, JOSHI ROHAN P, WESTLEY ANDREW, CARLSON MICHAEL, WILLIS CALEB, SCHLEICH: "AI-augmented histopathologic review using image analysis to optimize DNA yield and tumor purity from FFPE slides", ARXIV, 7 April 2022 (2022-04-07), XP093132536, [retrieved on 20240219]
SHAKER NADA, SARDANA RUHANI, HAMASAKI SATOSHI, NOHLE DAVID G., AYERS LEONA W., PARWANI ANIL V.: "Accuracy of whole slide image based image analysis is adversely affected by preanalytical factors such as stained tissue slide and paraffin block age", JOURNAL OF PATHOLOGY INFORMATICS, MEDKNOW PUBLICATIONS AND MEDIA PVT. LTD., IN, vol. 13, 1 January 2022 (2022-01-01), IN , pages 100121, XP093131690, ISSN: 2153-3539, DOI: 10.1016/j.jpi.2022.100121
OSINSKI BOLESŁAW L, BENTAIEB AÏCHA, HO IRVIN, JONES RYAN D, JOSHI ROHAN P, WESTLEY ANDREW, CARLSON MICHAEL, WILLIS CALEB, SCHLEICH: "AI-augmented histopathologic review using image analysis to optimize DNA yield and tumor purity from FFPE slides", ARXIV, 7 April 2022 (2022-04-07), XP093132536, [retrieved on 20240219]
SHAKER NADA, SARDANA RUHANI, HAMASAKI SATOSHI, NOHLE DAVID G., AYERS LEONA W., PARWANI ANIL V.: "Accuracy of whole slide image based image analysis is adversely affected by preanalytical factors such as stained tissue slide and paraffin block age", JOURNAL OF PATHOLOGY INFORMATICS, MEDKNOW PUBLICATIONS AND MEDIA PVT. LTD., IN, vol. 13, 1 January 2022 (2022-01-01), IN , pages 100121, XP093131690, ISSN: 2153-3539, DOI: 10.1016/j.jpi.2022.100121
Attorney, Agent or Firm:
BLT PATENT & LAW FIRM (KR)
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