APPARATUS FOR SCREENING PROPTEIN CRYSTALLIZATION CONDITIONS

Title:

APPARATUS FOR SCREENING PROPTEIN CRYSTALLIZATION CONDITIONS

Document Type and Number:

WIPO Patent Application WO/2004/097082

Kind Code:

A1

Abstract:

It is intended to provide an apparatus for screening protein crystallization conditions whereby protein crystallization conditions by the vapor diffusion method with the use of the sitting drop system can be efficiently screened. The above object is achieved as follows. Namely, an apparatus for screening protein crystallization conditions with the use of the sitting drop system (i.e., one of protein crystallization systems in the vapor diffusion methods), wherein a crystallization plate-constructing unit 2 having a means of injecting a protein solution and a crystallization solution into a well of a crystallization plate and a seal-putting means of sealing the well after the injection is connected to a protein crystal-detecting unit 5 of detecting protein crystals in the crystallization plate in a thermostatic chamber containing the crystallization plate in definite environment after the injection so as to automatically transfer the crystallization plate. Thus, screening can be efficiently and automatically performed.

Inventors:

MOTEGI ITSURO
MATSUZAKI HIROFUMI
KITAHARA HIDEYOSHI
TSUKAMOTO MITSUHAYA
SHIMOGAWA KOUJI
MAGOORI MASATAKA
HIGUCHI AKIRA

Application Number:

PCT/JP2004/006147

Publication Date:

November 11, 2004

Filing Date:

April 28, 2004

Export Citation:

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Assignee:

MATSUSHITA ELECTRIC IND CO LTD (JP)
MOTEGI ITSURO
MATSUZAKI HIROFUMI
KITAHARA HIDEYOSHI
TSUKAMOTO MITSUHAYA
SHIMOGAWA KOUJI
MAGOORI MASATAKA
HIGUCHI AKIRA

International Classes:

B01D9/02; C12M1/00; B01J4/02; C30B7/00; C30B29/58; (IPC1-7): C30B29/58

Foreign References:

JP2003502652A	2003-01-21
JPH07500806A	1995-01-26
JP2003014596A	2003-01-15

Other References: