Title:
APPARATUS FOR SIMULATING TRAUMATIC BRAIN INJURY AND METHOD FOR INDUCING SPINAL CORD INJURY
Document Type and Number:
WIPO Patent Application WO2000045773
Kind Code:
A3
Abstract:
This invention is an apparatus (20) for simulating human traumatic brain injury in an animal, said apparatus (20) comprising a support (21) having an aperture (22) having end walls (24), and side walls (26) disposed therein; a sliding element (28) sliding engaged with said side walls (26) of said aperture (22), said sliding element (28) having a retainer (30) disposed thereon for receiving an animal holder (32) therein; and a crank arm (34) operatively connected to both said sliding element (28), and an actuator mechanism (36). A method of simulating human spinal cord injury in an animal, said method comprising the steps of providing a vertebrate animal having an invertebral space, and a spinal cord; causing an opening in the animal at the invertebral space to the anterior surface of the spinal cord; inserting a deflated balloon embolectomy catheter into the opening; and rapidly inflating the balloon catheter to cause the balloon catheter to expand, and contact the spinal cord whereby the contact causes injury to the spinal cord.
Inventors:
MEYTHALER JAY M (US)
PEDUZZI JEAN (US)
PEDUZZI JEAN (US)
Application Number:
PCT/US2000/003182
Publication Date:
December 14, 2000
Filing Date:
February 08, 2000
Export Citation:
Assignee:
UAB RESEARCH FOUNDATION (US)
MEYTHALER JAY M (US)
PEDUZZI JEAN (US)
MEYTHALER JAY M (US)
PEDUZZI JEAN (US)
International Classes:
G09B23/28; (IPC1-7): A61B19/00
Foreign References:
| US4762130A | 1988-08-09 | |||
| US6066158A | 2000-05-23 |
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