APPARATUS FOR TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND ASSOCIATED METHOD

WIPO Patent Application WO2002018001

A3

An apparatus and method for treatment of a patient having a pulmonary disease involving chronic obstruction of the airways includes a container having therein a chamber containing a composition of L-tartrate in a pharmaceutically acceptable carrier; an opening connected to the chamber so as to provide an outlet thereof, the opening sized for producing droplets of a predetermined size range responsive to the composition being motivated from the chamber through the opening; and a source of motivating force connected with the chamber so as to motivate the compositions through the opening to thereby cause nebulization of the composition. A treatment kit comprises the container described and a mouthpiece connectable to the container so as to be in fluid connection with the opening and downstream therefrom to thereby convey the nebulized composition into a patient's mouth to thereby facilitate oral inhalation of the nebulized composition by the patient.

ADDINGTON ROBERT W
STEPHENS ROBERT
MILLER STUART

PCT/US2001/026939

July 25, 2002

August 30, 2001

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PNEUMOFLEX SYSTEMS L L C (US)

A61K9/00; A61M15/00; (IPC1-7): A61M15/00

WO1999049917A1	1999-10-07
WO1999036115A2	1999-07-22

US6004268A	1999-12-21
US5839430A	1998-11-24

FUJIMURA M ET AL: "SEX DIFFERENCE IN THE INHALED TARTARIC ACID COUGH THRESHOLD IN NON-ATOPIC HEALTHY SUBJECTS", THORAX, LONDON, GB, vol. 45, no. 8, August 1990 (1990-08-01), pages 633 - 634, XP002919151

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