Title:
APPLICATION OF OSI-906
Document Type and Number:
WIPO Patent Application WO/2022/206339
Kind Code:
A1
Abstract:
The present invention relates to the field of biological medicine, and provides an application of OSI-906. OSI-906 is a small molecular compound, which may inhibit the signal transduction, proliferation and cytokine secretion of a tyrosine kinase receptor IGF-1R in a human body, and which may be used for treating related diseases such as thyroid-related eye diseases, inflammatory skin diseases, generalized myxedema, pretibial myxedema, polycystic ovarian syndrome, hyperandrogenemia, endometriosis-related pain and systemic sclerosis.
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Inventors:
ZHANG PENG (CN)
MA LIN (CN)
GUO SHUHUA (CN)
MA LIN (CN)
GUO SHUHUA (CN)
Application Number:
PCT/CN2022/080328
Publication Date:
October 06, 2022
Filing Date:
March 11, 2022
Export Citation:
Assignee:
SUZHOU PRO HEAL PHARMACEUTICALS TECH CO LTD (CN)
International Classes:
A61K31/4985; A61P15/00; A61P17/00; A61P27/02; A61P29/00
Domestic Patent References:
| WO2021041773A1 | 2021-03-04 | |||
| WO2018077889A1 | 2018-05-03 |
Foreign References:
| CN113143928A | 2021-07-23 |
Other References:
SHEN MENG-QI, CHEN YONG-YAN;YUAN WEI;LEI WEI;LI LU: "A Case of Graves Disease Coexisted with Pretibial Myxedema", THE CHINESE JOURNAL OF DERMATOVENEREOLOGY, XI'AN JIAOTONG DAXUE, XI'AN, CN, vol. 27, no. 10, 31 October 2013 (2013-10-31), CN , XP055972405, ISSN: 1001-7089
MA XIAOHONG, HE SHENG-YU;XU XIAN;LI XIAO-RONG: "Research Progress of the Relationship Between Insulin-like Growth Factor and Follicular Development", CHINESE JOURNAL OF WOMAN AND CHILD HEALTH RESEARCH, vol. 27, no. 3, 31 December 2016 (2016-12-31), pages 409 - 411, XP055972408, ISSN: 1673-5293, DOI: 10.3969/j.issn.1673-5293.2016.03.044
ZHOU QING－PING, LUO HONG－YAN, SIMA NI: "Expressions and significance of serum CA125 VEGF and IGF－1 in patients with endometriosis", MATERNAL AND CHILD HEALTH CARE OF CHINA, vol. 32, no. 9, 31 May 2017 (2017-05-31), pages 1841 - 1844, XP055972413, ISSN: 1001-4411, DOI: 10.7620/zgfybj.j.issn.1001-4411.2017.09.05
DU WEI, LI YUN, MAO XIAO-FEI, ZHANG TAO, FANG KAI, SUN QIU-NING: "Relationship between Insulin-like Growth Factor and Patients with Systemic Sclerosis", MEDICAL JOURNAL OF PEKING UNION MEDICAL COLLEGE HOSPITAL, vol. 3, no. 4, 31 October 2012 (2012-10-31), pages 370 - 374, XP055972416, ISSN: 1674-9081, DOI: 10.3969/j.issn.1674-9081.2012.04.002
MA XIAOHONG, HE SHENG-YU;XU XIAN;LI XIAO-RONG: "Research Progress of the Relationship Between Insulin-like Growth Factor and Follicular Development", CHINESE JOURNAL OF WOMAN AND CHILD HEALTH RESEARCH, vol. 27, no. 3, 31 December 2016 (2016-12-31), pages 409 - 411, XP055972408, ISSN: 1673-5293, DOI: 10.3969/j.issn.1673-5293.2016.03.044
ZHOU QING－PING, LUO HONG－YAN, SIMA NI: "Expressions and significance of serum CA125 VEGF and IGF－1 in patients with endometriosis", MATERNAL AND CHILD HEALTH CARE OF CHINA, vol. 32, no. 9, 31 May 2017 (2017-05-31), pages 1841 - 1844, XP055972413, ISSN: 1001-4411, DOI: 10.7620/zgfybj.j.issn.1001-4411.2017.09.05
DU WEI, LI YUN, MAO XIAO-FEI, ZHANG TAO, FANG KAI, SUN QIU-NING: "Relationship between Insulin-like Growth Factor and Patients with Systemic Sclerosis", MEDICAL JOURNAL OF PEKING UNION MEDICAL COLLEGE HOSPITAL, vol. 3, no. 4, 31 October 2012 (2012-10-31), pages 370 - 374, XP055972416, ISSN: 1674-9081, DOI: 10.3969/j.issn.1674-9081.2012.04.002
Attorney, Agent or Firm:
JJS INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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