Title:
APPLICATION OF TANNIC ACID IN PREPARATION OF ANTI-RESPIRATORY VIRUS DRUG
Document Type and Number:
WIPO Patent Application WO/2022/036774
Kind Code:
A1
Abstract:
An application of tannic acid in preparation of an anti-respiratory virus drug. Experiments involving live viruses show that tannic acid has a significant inhibitory effect and a definite curative effect on respiratory viruses such as coronaviruses comprising SARS-CoV-2 and influenza A H1N1 viruses, and has a broad application prospect in the field of preparation of anti-respiratory virus drugs. Moreover, tannic acid exists in a variety of plants and is a natural active compound that exists in nature; in addition, tannic acid is also used as a food additive, has high safety, and provides a good basis for drug development.
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Inventors:
FU JUN (CN)
Application Number:
PCT/CN2020/114432
Publication Date:
February 24, 2022
Filing Date:
September 10, 2020
Export Citation:
Assignee:
SUNTRAP LIFE TECH LTD (CN)
International Classes:
A23K20/163; A61K31/7024; A23K50/20; A23K50/30; A23K50/40; A23K50/50; A23K50/70; A23L33/10; A61P31/14
Foreign References:
| CN105535012A | 2016-05-04 | |||
| JP2011084549A | 2011-04-28 | |||
| CN109745354A | 2019-05-14 |
Other References:
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KHALIFA IBRAHIM, ZHU WEI, MOHAMMED HAMMAD HAMED HAMMAD, DUTTA KUNAL, LI CHUNMEI: "Tannins inhibit SARS‐CoV‐2 through binding with catalytic dyad residues of 3CL pro : An in silico approach with 19 structural different hydrolysable tannins", JOURNAL OF FOOD BIOCHEMISTRY., WILEY-BLACKWELL PUBLISHING, INC., US, vol. 44, no. 10, 1 October 2020 (2020-10-01), US , XP055821275, ISSN: 0145-8884, DOI: 10.1111/jfbc.13432
XIAO LAN: "Fight against SARS and Stay Healthy", JOURNAL OF MEDICAL ECONOMICS, 28 May 2003 (2003-05-28), pages 1 - 2, XP009534223
MAHDIAN SOODEH, EBRAHIM-HABIBI AZADEH, ZARRABI MAHBOOBEH: "Drug repurposing using computational methods to identify therapeutic options for COVID-19", JOURNAL OF DIABETES & METABOLIC DISORDERS, vol. 19, no. 2, 1 December 2020 (2020-12-01), pages 691 - 699, XP055901371, DOI: 10.1007/s40200-020-00546-9
ZHOU YIBO, DOU WEN-YUAN;DUAN XING-CHUN;TI HUI-HUI: "Traditional Chinese Medicines Targeting Influenza Virus Replication: Research Progress", JOURNAL OF INTERNATIONAL PHARMACEUTICAL RESEARCH, JUNSHI YIXUE KEXUEYUAN * DUWU YAOWU JIANJIUSUO, CN, vol. 46, no. 5, 31 May 2019 (2019-05-31), CN , pages 332 - 338, XP055901373, ISSN: 1674-0440, DOI: 10.13220/j.cnki.jipr.2019.05.002
LI PING, CHANG XIAO-XIN: "The Effects of Resveratrol on Antibacterial and Antiviral Properties", CHINESE JOURNAL OF MICROECOLOGY, CHINESE PREVENTIVE MEDICINE ASSOCIATION; DALIAN MEDICAL UNIVERSITY, CN, vol. 26, no. 10, 31 October 2014 (2014-10-31), CN , pages 1215 - 1219, XP055901379, ISSN: 1005-376X, DOI: 10.13381/j.cnki.cjm.201410030
XIANG QIANWANG RUI: "Characteristics and prevention of coronavirus infection[J", CHINESE JOURNAL OF NOSOCOMIOLOGY, vol. 013, no. 011, 2003, pages 1097 - 1100
KHALIFA IBRAHIM, ZHU WEI, MOHAMMED HAMMAD HAMED HAMMAD, DUTTA KUNAL, LI CHUNMEI: "Tannins inhibit SARS‐CoV‐2 through binding with catalytic dyad residues of 3CL pro : An in silico approach with 19 structural different hydrolysable tannins", JOURNAL OF FOOD BIOCHEMISTRY., WILEY-BLACKWELL PUBLISHING, INC., US, vol. 44, no. 10, 1 October 2020 (2020-10-01), US , XP055821275, ISSN: 0145-8884, DOI: 10.1111/jfbc.13432
XIAO LAN: "Fight against SARS and Stay Healthy", JOURNAL OF MEDICAL ECONOMICS, 28 May 2003 (2003-05-28), pages 1 - 2, XP009534223
MAHDIAN SOODEH, EBRAHIM-HABIBI AZADEH, ZARRABI MAHBOOBEH: "Drug repurposing using computational methods to identify therapeutic options for COVID-19", JOURNAL OF DIABETES & METABOLIC DISORDERS, vol. 19, no. 2, 1 December 2020 (2020-12-01), pages 691 - 699, XP055901371, DOI: 10.1007/s40200-020-00546-9
ZHOU YIBO, DOU WEN-YUAN;DUAN XING-CHUN;TI HUI-HUI: "Traditional Chinese Medicines Targeting Influenza Virus Replication: Research Progress", JOURNAL OF INTERNATIONAL PHARMACEUTICAL RESEARCH, JUNSHI YIXUE KEXUEYUAN * DUWU YAOWU JIANJIUSUO, CN, vol. 46, no. 5, 31 May 2019 (2019-05-31), CN , pages 332 - 338, XP055901373, ISSN: 1674-0440, DOI: 10.13220/j.cnki.jipr.2019.05.002
LI PING, CHANG XIAO-XIN: "The Effects of Resveratrol on Antibacterial and Antiviral Properties", CHINESE JOURNAL OF MICROECOLOGY, CHINESE PREVENTIVE MEDICINE ASSOCIATION; DALIAN MEDICAL UNIVERSITY, CN, vol. 26, no. 10, 31 October 2014 (2014-10-31), CN , pages 1215 - 1219, XP055901379, ISSN: 1005-376X, DOI: 10.13381/j.cnki.cjm.201410030
XIANG QIANWANG RUI: "Characteristics and prevention of coronavirus infection[J", CHINESE JOURNAL OF NOSOCOMIOLOGY, vol. 013, no. 011, 2003, pages 1097 - 1100
Attorney, Agent or Firm:
YOGO PATENT AND TRADEMARK AGENCY LIMITED COMPANY (CN)
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