Title:
APTAMER, CONJUGATE, COMPOSITION, METHOD FOR PREPARING SAME, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/198201
Kind Code:
A1
Abstract:
Provided is an aptamer, comprising a continuous nucleotide sequence having a sequence set forth in formula (1). Also provided is a conjugate comprising: a delivery group formed by the aptamer, and a functional group. The aptamer provided herein can specifically target and internalize into a tumor cell. The conjugate provided can deliver the functional group to a tumor tissue in a targeted manner, so as to diagnose and/or treat tumors and tumor-related diseases.
Inventors:
WANG SHAN (CN)
LIANG ZICAI (CN)
ZHANG HONGYAN (CN)
GAO SHAN (CN)
HU XIN (CN)
LIANG ZICAI (CN)
ZHANG HONGYAN (CN)
GAO SHAN (CN)
HU XIN (CN)
Application Number:
PCT/CN2023/088466
Publication Date:
October 19, 2023
Filing Date:
April 14, 2023
Export Citation:
Assignee:
SUZHOU RIBO LIFE SCIENCE CO LTD (CN)
International Classes:
A61K48/00; A61P35/00; C12N15/113
Domestic Patent References:
| WO2017035340A1 | 2017-03-02 | |||
| WO2021204216A1 | 2021-10-14 |
Foreign References:
| CN110945132A | 2020-03-31 | |||
| CN110997919A | 2020-04-10 | |||
| CN102533770A | 2012-07-04 | |||
| CN108289906A | 2018-07-17 |
Attorney, Agent or Firm:
PEKSUNG INTELLECTUAL PROPERTY LTD. (CN)
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