Title:
AQUEOUS COMPOSITION CONTAINING EPINASTINE OR SALT THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/210646
Kind Code:
A1
Abstract:
The present invention provides an aqueous composition for enhancing transferability into ocular tissue, the aqueous composition containing epinastine or a salt thereof and a quaternary ammonium compound, wherein the content ratio of the quaternary ammonium compound with respect to the epinastine or salt thereof is 0.1 part by weight or less with respect to 1 part by weight of the content of the epinastine or salt thereof.
Inventors:
HAYASHI TAKESHI (JP)
MOMOKAWA YUSUKE (JP)
KIMURA HITOMI (JP)
KAWAZU KOICHI (JP)
MOMOKAWA YUSUKE (JP)
KIMURA HITOMI (JP)
KAWAZU KOICHI (JP)
Application Number:
PCT/JP2021/015601
Publication Date:
October 21, 2021
Filing Date:
April 15, 2021
Export Citation:
Assignee:
SANTEN PHARMACEUTICAL CO LTD (JP)
International Classes:
A61K31/55; A61K9/08; A61K47/16; A61P27/02
Domestic Patent References:
| WO2008098122A2 | 2008-08-14 |
Foreign References:
| JP2003514021A | 2003-04-15 |
Other References:
PAULY, A. ET AL.: "Multiple endpoint analysis of BAC-preserved and unpreserved antiallergic eye drops on a 3D-reconstituted corneal epithelial model", MOLECULAR VISION, vol. 17, 2011, pages 745 - 755, XP055868062
AKIYAMA, YOICHI ET AL.: "Effects of epinastine ophthalmal solution on corneal epithelial barrier function", ABSTRACTS OF THE GENERAL MEETING OF THE JAPANESE CORNEAL SOCIETY . THE JAPANESE SOCIETY OF CORNEAL TRANSPLANTATION PROGRAM, 2018, pages 83
AKIYAMA, YOICHI ET AL.: "Effects of epinastine ophthalmal solution on corneal epithelial barrier function", ABSTRACTS OF THE GENERAL MEETING OF THE JAPANESE CORNEAL SOCIETY . THE JAPANESE SOCIETY OF CORNEAL TRANSPLANTATION PROGRAM, 2018, pages 83
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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