Title:
AROMATIC AMINE COMPOUND AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/088291
Kind Code:
A1
Abstract:
Disclosed in the present invention are an aromatic amine compound and an application thereof. The aromatic amine compound can effectively inhibit the tyrosine kinase activity of Abelson protein (ABL1), Abelson related protein (ABL2) and related chimeric protein, especially BCR-ABL1, can be applied to prepare inhibitors for Abelson protein (ABL1), Abelson related protein (ABL2) and related chimeric protein, and is used as a drug for resisting BCR-ABL1 fusion protein activity abnormality-related diseases.
Inventors:
ZHANG YUHUI (CN)
Application Number:
PCT/CN2022/132214
Publication Date:
May 25, 2023
Filing Date:
November 16, 2022
Export Citation:
Assignee:
WUHAN ZHONGCHENG HEALTH BIO PHARM TECH CO LTD (CN)
International Classes:
A61K31/33; C07D401/14; A61K31/395; A61K31/4155; A61K31/435; A61K31/4439; A61K31/444; A61K31/506; A61P35/00; A61P35/02; A61P37/00; C07D401/02; C07D401/04; C07D403/02; C07D403/04; C07D403/14
Foreign References:
| CN104302638A | 2015-01-21 | |||
| CN109790144A | 2019-05-21 | |||
| CN104379574A | 2015-02-25 | |||
| CN109651359A | 2019-04-19 | |||
| CN1597668A | 2005-03-23 | |||
| CN112300129A | 2021-02-02 |
Attorney, Agent or Firm:
WUHAN GENUIRY INTELLECTUAL PROPERTY FIRM (GENERAL PARTNER) (CN)
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