Title:
AROMATIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/217148
Kind Code:
A1
Abstract:
Disclosed are an aromatic compound, a method for preparing same, and use thereof. Specifically, the present application discloses a compound represented by formula I or a pharmaceutically acceptable salt thereof and use thereof. The aromatic compound can be used as a protease degradation agent and/or inhibitor, and has a good degradation and/or inhibition effect on KRAS, especially KRAS G12C.
Inventors:
XIANG JASON SHAOYUN (CN)
WANG SUYUE (CN)
LV ZHIJIAN (CN)
YANG SHUAI (CN)
FANG QI (CN)
HUANG TAO (CN)
YANG RUI (CN)
WANG SUYUE (CN)
LV ZHIJIAN (CN)
YANG SHUAI (CN)
FANG QI (CN)
HUANG TAO (CN)
YANG RUI (CN)
Application Number:
PCT/CN2023/093039
Publication Date:
November 16, 2023
Filing Date:
May 09, 2023
Export Citation:
Assignee:
HANGZHOU POLYMED BIOPHARMACEUTICALS INC (CN)
International Classes:
C07D401/14; A61K31/435; A61K31/495; A61P35/00; C07D403/14
Domestic Patent References:
| WO2021051034A1 | 2021-03-18 | |||
| WO2022111521A1 | 2022-06-02 | |||
| WO2022111513A1 | 2022-06-02 | |||
| WO2021248079A1 | 2021-12-09 |
Foreign References:
| CN113061132A | 2021-07-02 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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