Title:
ARTIFICIAL IMMUNOSURVEILLANCE CHIMERIC ANTIGEN RECEPTOR (AI-CAR) AND CELLS EXPRESSING THE SAME
Document Type and Number:
WIPO Patent Application WO/2020/172643
Kind Code:
A3
Abstract:
The application provides non-viral vector, comprising an artificial immunosurveillance chimeric antigen receptor (AI-CAR) expression cassette flanked by two transposons or viral terminal repeats (IR), wherein the AI-CAR expression cassette comprises an inducible gene expression unit and a CAR expression unit.
Inventors:
LUK JOHN M (US)
STAUNTON DONALD E (US)
STAUNTON DONALD E (US)
LUK JOHN M (US)
HARLAN JOHN M (US)
STAUNTON DONALD E (US)
STAUNTON DONALD E (US)
LUK JOHN M (US)
HARLAN JOHN M (US)
Application Number:
PCT/US2020/019376
Publication Date:
November 12, 2020
Filing Date:
February 21, 2020
Export Citation:
Assignee:
LUK JOHN M (US)
STAUNTON DONALD E (US)
STAUNTON DONALD E (US)
International Classes:
A61K35/17; A61K38/00; A61P35/00
Domestic Patent References:
| WO2017075537A1 | 2017-05-04 | |||
| WO2016130598A1 | 2016-08-18 | |||
| WO2015052538A1 | 2015-04-16 | |||
| WO2020172641A1 | 2020-08-27 |
Attorney, Agent or Firm:
HAN, Zhihua (US)
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