ARTIFICIAL SKIN MIMICKING PAPILLAE LAYER STRUCTURE AND MANUFACTURING METHOD THEREFOR

Title:

ARTIFICIAL SKIN MIMICKING PAPILLAE LAYER STRUCTURE AND MANUFACTURING METHOD THEREFOR

Document Type and Number:

WIPO Patent Application WO/2023/113324

Kind Code:

A1

Abstract:

The present invention relates to artificial skin including gelatin methacrylate and hyaluronic acid methacrylate as main components and fabricated to have the interface between the epidermis-mimicked layer and the dermis-mimicked layer in a curved shape. With improved cytocompatibility for epidermal cells, dermal cells, and hair follicle cells, the artificial skin can allow for improvement in proliferating the cells and developing functions of the cells.

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Inventors:

HAN DONG WOOK (KR)
KIM KI SU (KR)
KANG MOON SUNG (KR)
KWON MINA (KR)

Application Number:

PCT/KR2022/019488

Publication Date:

June 22, 2023

Filing Date:

December 02, 2022

Export Citation:

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Assignee:

NAT UNIV PUSAN IND UNIV COOP FOUND (KR)

International Classes:

A61L27/60; A61F2/10; A61L27/20; A61L27/22; A61L27/38; A61L27/52

Foreign References:

JP3951148B2	2007-08-01
KR20200096780A	2020-08-13
KR102201030B1	2021-01-11
US20050089512A1	2005-04-28

Other References:

SHEN ZHIZHONG; CAO YANYAN; LI MENG; YAN YAYUN; CHENG RONG; ZHAO YAJING; SHAO QUAN; WANG JIANMING; SANG SHENGBO: "Construction of tissue-engineered skin with rete ridges using co-network hydrogels of gelatin methacrylated and poly(ethylene glycol) diacrylate", MATERIALS SCIENCE AND ENGINEERING C, ELSEVIER SCIENCE S.A., CH, vol. 129, 9 August 2021 (2021-08-09), CH , XP086797391, ISSN: 0928-4931, DOI: 10.1016/j.msec.2021.112360
CAMCI-UNAL GULDEN, CUTTICA DAVIDE, ANNABI NASIM, DEMARCHI DANILO, KHADEMHOSSEINI ALI: "Synthesis and Characterization of Hybrid Hyaluronic Acid-Gelatin Hydrogels", BIOMACROMOLECULES, AMERICAN CHEMICAL SOCIETY, US, vol. 14, no. 4, 8 April 2013 (2013-04-08), US , pages 1085 - 1092, XP093071947, ISSN: 1525-7797, DOI: 10.1021/bm3019856

Attorney, Agent or Firm:

IPCJ PATENT & LAW FIRM (KR)

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