ARTIFICIAL TISSUE MODEL COMPRISING HYDROGEL STRUCTURE HAVING MICROCHANNEL NETWORK FORMED THEREIN

Title:

ARTIFICIAL TISSUE MODEL COMPRISING HYDROGEL STRUCTURE HAVING MICROCHANNEL NETWORK FORMED THEREIN

Document Type and Number:

WIPO Patent Application WO/2020/197326

Kind Code:

A1

Abstract:

The present invention relates to an artificial tissue model using a hydrogel structure having a microchannel network formed therein, through which a fluid can flow, and a disease model using same. The artificial tissue model makes it possible to culture cells in three dimensions in a similar way to an in vivo environment, and can also be usefully used as an artificial disease model by perfusing a component which induces a target disease through a hydrogel structure.

Inventors:

SUNG HAK JOON (KR)
LEE JUNG BOK (KR)

Application Number:

PCT/KR2020/004217

Publication Date:

October 01, 2020

Filing Date:

March 27, 2020

Export Citation:

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Assignee:

UNIV INDUSTRY FOUNDATION YONSEI UNIV (KR)

International Classes:

C12N5/071; A01K67/027; C12M3/00

Foreign References:

US20180002658A1	2018-01-04
US20120058174A1	2012-03-08

Other References:

HUH, DONGEUN, HUMAN ON A CHIP. CONVERGENCE RESEARCH REVIEW., vol. 1, no. 7, 5 October 2015 (2015-10-05), pages 5 - 28
BERTASSONI, L. E., HYDROGEL BIOPRINTED MICROCHANNEL NETWORKS FOR VASCULARIZATION OF TISSUE ENGINEERING CONSTRUCTS, 2014, pages 2202 - 2211, XP055562319
WU, W.: "Omnidirectional printing of 3D microvascular networks", ADVANCED HEALTHCARE MATERIALS, 2011, pages H178 - H183, XP055453902, DOI: 10.1002/adma.201004625

Attorney, Agent or Firm:

DANA PATENT LAW FIRM (KR)

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