Title:
ARYL OR HETEROARYL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF KINASE-RELATED DISEASE
Document Type and Number:
WIPO Patent Application WO/2022/015051
Kind Code:
A1
Abstract:
The present invention relates to an aryl or heteroaryl derivative and a pharmaceutical composition comprising same as an active ingredient for treatment of kinase-related disease. An aryl or heteroaryl derivative provided according to an aspect of the present invention exhibits an excellent inhibitory activity against kinases, especially receptor-interacting serine/threonine-protein kinase 1 (RIPK1) and as such, can be used as a therapeutic agent for RIPK1-related disease.
Inventors:
JO SEOHYUN (KR)
KIM SEUNGSU (KR)
CHOI HYEONJIN (KR)
MA DAHOON (KR)
RYU HEESUN (KR)
KIM DAMI (KR)
KIM SOOCHAN (KR)
CHOI JIEUN (KR)
HWANG HYEMIN (KR)
KIM UNHEE (KR)
LEE YOHAN (KR)
LEE HONG (KR)
JUNG HONGRYUL (KR)
KIM YEONSIL (KR)
KIM SUNGHWAN (KR)
SON JUNGBEOM (KR)
KIM NAM DOO (KR)
KIM SEUNGSU (KR)
CHOI HYEONJIN (KR)
MA DAHOON (KR)
RYU HEESUN (KR)
KIM DAMI (KR)
KIM SOOCHAN (KR)
CHOI JIEUN (KR)
HWANG HYEMIN (KR)
KIM UNHEE (KR)
LEE YOHAN (KR)
LEE HONG (KR)
JUNG HONGRYUL (KR)
KIM YEONSIL (KR)
KIM SUNGHWAN (KR)
SON JUNGBEOM (KR)
KIM NAM DOO (KR)
Application Number:
PCT/KR2021/009049
Publication Date:
January 20, 2022
Filing Date:
July 14, 2021
Export Citation:
Assignee:
VORONOIBIO CO LTD (KR)
VORONOI CO LTD (KR)
VORONOI CO LTD (KR)
International Classes:
C07D413/14; A61K31/4439; A61K31/497; A61K31/506; A61K31/5377; A61P1/00; A61P19/02; A61P25/28; A61P29/00; C07D413/12
Domestic Patent References:
| WO2018035072A1 | 2018-02-22 | |||
| WO2018183122A1 | 2018-10-04 |
Foreign References:
| US20140228367A1 | 2014-08-14 | |||
| US20180353480A1 | 2018-12-13 | |||
| US20140213592A1 | 2014-07-31 | |||
| KR20200089219A | 2020-07-24 |
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (KR)
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