Title:
ATR INHIBITOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/268025
Kind Code:
A1
Abstract:
Provided are a new class of compounds having an ATR inhibitory effect and as represented by formula I, and the use thereof in the preparation of a drug.
Inventors:
XIANG YONGZHE (CN)
LI LI (CN)
DAI HUAZHOU (CN)
LIU HUA (CN)
WU XIANQIANG (CN)
SUN WENBO (CN)
CHEN HONG (CN)
WANG YING (CN)
LI LI (CN)
DAI HUAZHOU (CN)
LIU HUA (CN)
WU XIANQIANG (CN)
SUN WENBO (CN)
CHEN HONG (CN)
WANG YING (CN)
Application Number:
PCT/CN2022/099809
Publication Date:
December 29, 2022
Filing Date:
June 20, 2022
Export Citation:
Assignee:
CHENGDU EASTON BIOPHARMACEUTICALS CO LTD (CN)
International Classes:
C07D413/14; A61K31/519; A61P35/00; C07D417/14
Domestic Patent References:
| WO2022152229A1 | 2022-07-21 |
Foreign References:
| CN101675051A | 2010-03-17 | |||
| CN102459272A | 2012-05-16 | |||
| CN101511840A | 2009-08-19 |
Other References:
LU, Y. P. ET AL.: "Rationally Designed PI3Kα Mutants to Mimic ATR and Their Use to Understand Binding Specificity of ATR Inhibitors", JOURNAL OF MOLECULAR BIOLOGY, vol. 429, 20 April 2017 (2017-04-20), XP085041884, DOI: 10.1016/j.jmb.2017.04.006
Attorney, Agent or Firm:
BEIJING SUNHOPE INTELLECTUAL PROPERTY LTD. (CN)
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