Title:
ATTENUATED DENGUE-3 VIRUS VACCINE
Document Type and Number:
WIPO Patent Application WO2000057904
Kind Code:
B1
Abstract:
The present invention provides vaccine compositions of attenuated dengue-3 virus. More specifically, the attenuated virus is produced by serial passage in PDK cells. The invention also provides methods for stimulating the immune system of an individual to induce protection against dengue-3 virus by administration of attenuated dengue-3 virus.
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Inventors:
ECKELS KENNETH H (US)
PUTNAK JOSEPH R (US)
DUBOIS DORIA R (US)
INNIS BRUCE L (US)
HOKE CHARLES H (US)
VAUGHN DAVID (US)
PUTNAK JOSEPH R (US)
DUBOIS DORIA R (US)
INNIS BRUCE L (US)
HOKE CHARLES H (US)
VAUGHN DAVID (US)
Application Number:
PCT/US2000/008134
Publication Date:
February 22, 2001
Filing Date:
March 24, 2000
Export Citation:
Assignee:
US ARMY (US)
ECKELS KENNETH H (US)
PUTNAK JOSEPH R (US)
DUBOIS DORIA R (US)
INNIS BRUCE L (US)
HOKE CHARLES H (US)
VAUGHN DAVID (US)
ECKELS KENNETH H (US)
PUTNAK JOSEPH R (US)
DUBOIS DORIA R (US)
INNIS BRUCE L (US)
HOKE CHARLES H (US)
VAUGHN DAVID (US)
International Classes:
C12N15/09; A61K39/12; A61K39/39; A61P31/12; A61P31/14; C12N7/04; C12N7/08; (IPC1-7): A61K39/12; A61P31/14; C12N7/08; C12N15/40
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