Title:
AUTOMATED CYTOLOGICAL SPECIMEN CLASSIFICATION SYSTEM AND METHOD
Document Type and Number:
WIPO Patent Application WO1995022749
Kind Code:
A3
Abstract:
A semi-automated method of classifying a specimen for the presence of premalignant or malignant cells, including the steps of treating a specimen with an immunochemical marker to provide a visual indication of cell proliferation, ranking individual objects in the specimen in an order according to the likelihood that each object has attributes consistent with a premalignant or malignant cell or cell cluster, selecting for display a set of said objects according to said ranking, and displaying images of said selected objects to facilitate review by an operator.
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Inventors:
RUTENBERG MARK R
RUTENBERG AKIVA
KOK LANBRECHT PIET
BOON MATHILDE ELISABETH
MANGO LAURIE J
RUTENBERG AKIVA
KOK LANBRECHT PIET
BOON MATHILDE ELISABETH
MANGO LAURIE J
Application Number:
PCT/US1995/000853
Publication Date:
September 14, 1995
Filing Date:
January 23, 1995
Export Citation:
Assignee:
NEUROMEDICAL SYSTEMS INC (US)
International Classes:
G01N33/483; G01N33/569; G01N33/574; G06F19/00; G01N1/44; G01N3/06; (IPC1-7): G01N/
Foreign References:
| US4965725A | 1990-10-23 | |||
| US5257182A | 1993-10-26 | |||
| US5235522A | 1993-08-10 |
Other References:
MDDI REPORTS GRAY SHEET, issued 23 September 1991, "NeoPath AutoPap 300 Designed to Analyze Pap Smears without Cytologist", page 16.
ANALYTICAL AND QUATITATIVE CYTOLOGY AND HISTOLOGY, Volume 13, No. 1, issued February 1991, M.S. WACHTEL et al., "Automated Analysis of Rat Breast Tumors", pages 69-73.
ACTA CYTOLOGICA: THE JOURNAL OF CLINICAL CYTOLOGY AND CYTOPATHOLOGY, Volume 32, No. 2, issued 04 April 1988, F.M. GAVIN et al., "Morphometric Differences Between Cytologically Benign and Malignant Serous Effusions", pages 175-182.
PROCEEDINGS OF THE NINTH ANNUAL CONFERENCE OF THE ENGINEERING IN MEDICINE AND BIOLOGICAL SOCIETY, issued 04 December 1987, D. TIEN et al., "Automated Cervical Smear Classification", pages 1-2.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, Volume 41, No. 9, issued 22 September 1994, F. ERCAL et al., "Neural Network Diagnosis of Malignant Melanoma from Color Images", pages 837-645.
ANALYTICAL AND QUATITATIVE CYTOLOGY AND HISTOLOGY, Volume 13, No. 1, issued February 1991, M.S. WACHTEL et al., "Automated Analysis of Rat Breast Tumors", pages 69-73.
ACTA CYTOLOGICA: THE JOURNAL OF CLINICAL CYTOLOGY AND CYTOPATHOLOGY, Volume 32, No. 2, issued 04 April 1988, F.M. GAVIN et al., "Morphometric Differences Between Cytologically Benign and Malignant Serous Effusions", pages 175-182.
PROCEEDINGS OF THE NINTH ANNUAL CONFERENCE OF THE ENGINEERING IN MEDICINE AND BIOLOGICAL SOCIETY, issued 04 December 1987, D. TIEN et al., "Automated Cervical Smear Classification", pages 1-2.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, Volume 41, No. 9, issued 22 September 1994, F. ERCAL et al., "Neural Network Diagnosis of Malignant Melanoma from Color Images", pages 837-645.
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