Title:
AUTOMATION MECHANISM FOR PRE/CLINICAL PRODUCTION OF RESORBABLE NERVE GUIDES
Document Type and Number:
WIPO Patent Application WO/2020/214328
Kind Code:
A3
Abstract:
The presently disclosed subject matter relates to systems for making an implantable construct comprising a reservoir coupled to the at least one frame; a mandrel base coupled to the at least one frame; a mandrel coupled to the mandrel base; a first mechanism configured to be coupled to the at least one frame and configured to move the at least one frame along a first axis; a second mechanism configured to be coupled to the at least one frame and configured to rotate the least one mandrel base along a second axis between a first orientation and a second orientation; and a container configured to be coupled to the at least one frame and configured to receive the mandrel in the second orientation. The disclosed mechanisms can manually, semi-automatically, or automatically control the movements of the at least one frame, reservoir, mandrel, mandrel base, and container to produce the construct with a lumen. The presently disclosed subject matter also relates to methods for making the construct.
Inventors:
REPKO ALEXANDER JAMES (US)
MARRA KACEY GRIBBIN (US)
SCHILLING BENJAMIN (US)
MARRA KACEY GRIBBIN (US)
SCHILLING BENJAMIN (US)
Application Number:
PCT/US2020/023708
Publication Date:
December 24, 2020
Filing Date:
March 19, 2020
Export Citation:
Assignee:
UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US)
REPKO ALEXANDER JAMES (US)
MARRA KACEY GRIBBIN (US)
REPKO ALEXANDER JAMES (US)
MARRA KACEY GRIBBIN (US)
International Classes:
A61L27/50; A61L27/00
Foreign References:
| US3166791A | 1965-01-26 | |||
| US4863668A | 1989-09-05 | |||
| US2090528A | 1937-08-17 | |||
| US20130189435A1 | 2013-07-25 | |||
| US20180112167A1 | 2018-04-26 | |||
| US7780897B2 | 2010-08-24 | |||
| US8366770B2 | 2013-02-05 |
Attorney, Agent or Firm:
LEE, Sandra, S. (US)
Download PDF: