Title:
AXIS-ASYMMETRIC OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT, AND PROCESS FOR PRODUCTION OF α-AMINO ACID OR DERIVATIVE THEREOF USING THE QUATERNARY AMMONIUM SALT
Document Type and Number:
WIPO Patent Application WO/2007/013697
Kind Code:
A1
Abstract:
Disclosed is a chiral phase-transfer catalyst having a simplified structure, which can be produced by reacting a 2,2'-dimethylenebromide-1,1'-binaphthyl derivative (which can be produced in relatively small numbers of steps) with a secondary amine (which is readily available). The catalyst is a compound represented by the formula (I) having a long-chain alkyl group R7 in its chemical structure. The catalyst is expected to show a high stereoselectivity even in a reaction where a conventional catalyst does not show a satisfactory stereoselectivity such as an asymmetric alkylation reaction.
Inventors:
MARUOKA KEIJI (JP)
MATSUMOTO JUN (JP)
MATSUMOTO JUN (JP)
Application Number:
PCT/JP2006/315456
Publication Date:
February 01, 2007
Filing Date:
July 28, 2006
Export Citation:
Assignee:
NAGASE & CO LTD (JP)
MARUOKA KEIJI (JP)
MATSUMOTO JUN (JP)
MARUOKA KEIJI (JP)
MATSUMOTO JUN (JP)
International Classes:
C07D223/14; B01J31/02; C07C249/02; C07C251/24; C07B53/00; C07B61/00
Domestic Patent References:
| WO2005056543A2 | 2005-06-23 | |||
| WO2006054366A1 | 2006-05-26 | |||
| WO2005073196A1 | 2005-08-11 |
Foreign References:
| JP2001048866A | 2001-02-20 | |||
| JP2002326992A | 2002-11-15 |
Other References:
BULMAN PAGE P.C. ET AL.: "Iminium Salt Catalysts for Asymmetric Epoxidation: The First High Enantio-selectivities", ORGANIC LETTERS, vol. 6, no. 10, 2004, pages 1543 - 1546, XP003007396
Attorney, Agent or Firm:
NANJO, Hiromichi (Okina Bldg. 2-9, Nishitenma 3-chome, Kita-k, Osaka-shi Osaka 47, JP)
Download PDF: