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Title:
AZA-FUSED RING COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE
Document Type and Number:
WIPO Patent Application WO/2024/067660
Kind Code:
A1
Abstract:
The present disclosure relates to an aza-fused ring compound, a preparation method therefor, and a use thereof in medicine. Specifically, the present disclosure relates to an aza-fused ring compound represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing said compound, and a use thereof as a phosphodiesterase (PDEs) inhibitor, in particular a use in the preparation of a medicament for the treatment and/or prevention of diseases or conditions mediated by PDE4 enzymes.

Inventors:
PENG CHENG (CN)
QIAN MENGFEI (CN)
LING WEIKANG (CN)
WU JIN (CN)
GAO FAN (CN)
YUAN SHUAI (CN)
SONG GUOWEI (CN)
YE JUNMIN (CN)
Application Number:
PCT/CN2023/121867
Publication Date:
April 04, 2024
Filing Date:
September 27, 2023
Export Citation:
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Assignee:
SUZHOU ARKBIOPHARMACEUTICAL CO LTD (CN)
International Classes:
C07D495/04; A61K31/519; A61K31/5377; A61K31/573; A61P1/00; A61P11/00; A61P25/00; A61P27/02; A61P29/00; C07D413/14; C07D519/00
Domestic Patent References:
WO2009053268A12009-04-30
WO2010114971A12010-10-07
Foreign References:
US20110046096A12011-02-24
CN101163706A2008-04-16
CN101426505A2009-05-06
CN103889970A2014-06-25
CN101827852A2010-09-08
CN111712502A2020-09-25
CN111108109A2020-05-05
Attorney, Agent or Firm:
SUZHOU JINSHANG INTELLECTUAL PROPERTY LAW FIRM (GENERAL PARTNERSHIP) (CN)
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