Title:
AZA-QUINOLINE COMPOUNDS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/057853
Kind Code:
A1
Abstract:
Provided aza-quinoline compounds of Formula (I), pharmaceutical compositions comprising such compounds; and the use of such compounds for treating a disease or condition mediated by Enhancer of Zeste Homolog 2 (EZH2), Polycomb Repressive Complex 2 (PRC2), or a combination thereof.
Inventors:
LI LING (CN)
DAI XUAN (CN)
DORE MICHAEL (CA)
GU XIANG-JU JUSTIN (CN)
LIU KEVIN KUN CHIN (CN)
MAK SING YEUNG FRANKIE (SG)
MI YUAN (CN)
OYANG COUNDE (US)
PAPILLON JULIEN (US)
QI WEI (VICKY) (CN)
YAN XIAOXIA (CN)
YU ZHENGTIAN (CN)
ZHANG JI YUE (JEFF) (CN)
ZHAO KEHAO (US)
DAI XUAN (CN)
DORE MICHAEL (CA)
GU XIANG-JU JUSTIN (CN)
LIU KEVIN KUN CHIN (CN)
MAK SING YEUNG FRANKIE (SG)
MI YUAN (CN)
OYANG COUNDE (US)
PAPILLON JULIEN (US)
QI WEI (VICKY) (CN)
YAN XIAOXIA (CN)
YU ZHENGTIAN (CN)
ZHANG JI YUE (JEFF) (CN)
ZHAO KEHAO (US)
Application Number:
PCT/CN2020/117487
Publication Date:
April 01, 2021
Filing Date:
September 24, 2020
Export Citation:
Assignee:
NOVARTIS AG (CH)
LI LING (CN)
LI LING (CN)
International Classes:
A61K31/435; C07D403/14; A61K31/505; A61P35/00; C07D401/14
Domestic Patent References:
| WO2016103155A1 | 2016-06-30 | |||
| WO2017221100A1 | 2017-12-28 | |||
| WO2017221092A1 | 2017-12-28 | |||
| WO2017002064A1 | 2017-01-05 |
Other References:
See also references of EP 4034535A4
Attorney, Agent or Firm:
ZHONGZI LAW OFFICE (CN)
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