Title:
AZABICYCYCLIC COMPOUNDS FOR RELIEVING PAIN AND TREATING CENTRAL NERVOUS SYSTEM DISORDERS
Document Type and Number:
WIPO Patent Application WO2005037832
Kind Code:
B1
Abstract:
Patients susceptible to or suffering from disorders, such as central nervous system disorders, which are characterized by an alteration in normal neurotransmitter release, such as dopamine release (e.g., Parkinsonism, Parkinson's Disease, Tourette's Syndrome, attention deficient disorder, or schizophrenia), are treated by administering a compound of Formulas (1 or 2), as described herein. The compounds of Formulas (1 and 2) are also useful for treating pain, and treating drug addiction, nicotine addiction, and/or obesity. The compounds can exist as individual stereoisomers, racemic mixtures, diastereomers and the like.
Inventors:
BREINING SCOTT R (US)
BHATTI BALWINDER S (US)
HAWKINS GREGORY D (US)
MIAO LAN (US)
MAZUROV ANATOLY (US)
PHILLIPS TERESA Y (US)
MILLER CRAIG H (US)
BHATTI BALWINDER S (US)
HAWKINS GREGORY D (US)
MIAO LAN (US)
MAZUROV ANATOLY (US)
PHILLIPS TERESA Y (US)
MILLER CRAIG H (US)
Application Number:
PCT/US2004/034051
Publication Date:
September 15, 2005
Filing Date:
October 15, 2004
Export Citation:
Assignee:
TARGACEPT INC (US)
BREINING SCOTT R (US)
BHATTI BALWINDER S (US)
HAWKINS GREGORY D (US)
MIAO LAN (US)
MAZUROV ANATOLY (US)
PHILLIPS TERESA Y (US)
MILLER CRAIG H (US)
BREINING SCOTT R (US)
BHATTI BALWINDER S (US)
HAWKINS GREGORY D (US)
MIAO LAN (US)
MAZUROV ANATOLY (US)
PHILLIPS TERESA Y (US)
MILLER CRAIG H (US)
International Classes:
A61K31/46; A61K31/506; C07D221/22; C07D401/04; (IPC1-7): C07D401/04; A61K31/403; A61P25/00
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