Title:
BACTERIOPHAGE COMPOSITION
Document Type and Number:
WIPO Patent Application WO2003077953
Kind Code:
A3
Abstract:
The present invention provides a composition which comprises a complex of a bacteriophage and a cationic delivery moiety, such as a cationic polymer, in particular a cationic peptoid or a cationic peptide. More specifically, the present invention provides a composition comprising a complex of a bacteriophage and a delivery peptide or a protective or stabilising peptide. The present invention further provides a method for the delivery of bacteriophage across a membrane, such as a cell membrane; and a method for the treatment of bacterial infection, in particular intracellular bacterial infection, using a complex according to the invention.
Inventors:
WEST DAVID (GB)
PASECHNIK VLADIMIR DI
PASECHNIK VLADIMIR DI
Application Number:
PCT/GB2003/001035
Publication Date:
January 08, 2004
Filing Date:
March 12, 2003
Export Citation:
Assignee:
PHAGE GENOMICS INC (GB)
WEST DAVID (GB)
POLYANSKAYA NATASHA HF (GB)
WEST DAVID (GB)
POLYANSKAYA NATASHA HF (GB)
International Classes:
A61K47/48; (IPC1-7): A61K47/48
Domestic Patent References:
| WO1994024959A1 | 1994-11-10 | |||
| WO2001037807A1 | 2001-05-31 | |||
| WO2000061190A2 | 2000-10-19 | |||
| WO1999010014A2 | 1999-03-04 |
Foreign References:
| US5804604A | 1998-09-08 | |||
| US5688501A | 1997-11-18 |
Other References:
POOGA M ET AL: "Cell penetration by transportan.", THE FASEB JOURNAL: OFFICIAL PUBLICATION OF THE FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY. UNITED STATES JAN 1998, vol. 12, no. 1, January 1998 (1998-01-01), pages 67 - 77, XP002219568, ISSN: 0892-6638
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