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Title:
BASIDIOMYCETOUS YEAST AND METHOD FOR REDUCING CARBON CATABOLITE REPRESSION OF BASIDIOMYCETOUS YEAST
Document Type and Number:
WIPO Patent Application WO/2023/190542
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a mutant of a basidiomycetous yeast such as P. antarctica, the mutant having reduced carbon catabolite repression. The present invention pertains to basidiomycetous yeasts in which glucokinase gene includes a hypomorphic mutation. The present invention also pertains to a method for reducing the carbon catabolite repression of a basidiomycetous yeast, the method including a step for suppressing the function of glucokinase of the basidiomycetous yeast.

Inventors:
TANAKA MIZUKI (JP)
KITAMOTO HIROKO (JP)
TANAKA TAKUMI (JP)
MIURA ATSUHIRO (JP)
Application Number:
PCT/JP2023/012566
Publication Date:
October 05, 2023
Filing Date:
March 28, 2023
Export Citation:
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Assignee:
NAT AGRICULTURE & FOOD RES ORG (JP)
NATIONAL UNIV CORPORATION TOKYO UNIV OF AGRICULTURE AND TECHNOLOGY (JP)
International Classes:
C12N1/19; C12N15/54; C12P21/00
Foreign References:
JP2018157814A2018-10-11
Other References:
RENÉ DE MOT; HUBERT VERACHTERT : "Regulation of the amylase secretion by the yeastand a 2-deoxy--glucose resistant mutant", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER, BERLIN, DE, vol. 26, no. 3, 1 June 1987 (1987-06-01), Berlin, DE , pages 258 - 262, XP035168878, ISSN: 1432-0614, DOI: 10.1007/BF00286320
TANAKA, TAKUMI; MIURA, ATSUHIRO; TANAKA, MIZUKI; KITAMOTO, HIROKO: "4C08-02 Identification and functional analysis of the C2H2 transcription factor Mig1 from the basidiomycetous yeast Pseudozyma antarctica", PROCEEDINGS OF THE 2022 ANNUAL MEETING OF JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY (JSBBA 2022); MARCH 15-18, 2022, 5 March 2022 (2022-03-05) - 18 March 2022 (2022-03-18), pages 1095, XP009549367
TANAKA MIZUKI: " Analysis of the regulatory mechanism of hydrolase production by glucose kinase in filamentous fungi.", REPORT ON RESEARCH RESULT OF GRANTS-IN-AID FOR SCIENTIFIC RESEARCH, 1 January 2021 (2021-01-01), XP093094769, Retrieved from the Internet [retrieved on 20231025]
GUZMÁN SILVIA, CARMONA ALONSO, ESCALANTE LAURA, IMRISKOVA IVETA, LÓPEZ RUTH, RODRÍGUEZ-SANOJA ROMINA, RUIZ BEATRIZ, SERVÍN-GONZÁLE: "Pleiotropic effect of the SCO2127 gene on the glucose uptake, glucose kinase activity and carbon catabolite repression in Streptomyces peucetius var. caesius", MICROBIOLOGY, SOCIETY FOR GENERAL MICROBIOLOGY, READING, vol. 151, no. 5, 1 May 2005 (2005-05-01), Reading , pages 1717 - 1723, XP093094422, ISSN: 1350-0872, DOI: 10.1099/mic.0.27557-0
Attorney, Agent or Firm:
TANAKA Shinichiro et al. (JP)
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