Title:
BENDAMUSTINE LIQUID PREPARATION
Document Type and Number:
WIPO Patent Application WO/2021/161876
Kind Code:
A1
Abstract:
A bendamustine liquid preparation comprising a liquid composition and a container in which the liquid composition is enclosed, in which the liquid composition comprises bendamustine or a salt thereof, polyethylene glycol, and at least one component selected from the group consisting of ascorbic acid, an ascorbic acid derivative and a salt of ascorbic acid or the ascorbic acid derivative in which the total content of propylene glycol and glycerin is less than 1% by mass relative to the whole mass of the liquid composition, and the oxygen concentration in a gas in the container is 10% by volume or less or the ratio of the number of molecules of oxygen to the number of molecules of bendamustine or a salt thereof in the bendamustine liquid preparation is 0.10 or less.
Inventors:
HASHIMOTO SHINICHI (JP)
Application Number:
PCT/JP2021/003981
Publication Date:
August 19, 2021
Filing Date:
February 03, 2021
Export Citation:
Assignee:
FUJIFILM CORP (JP)
International Classes:
A61K9/08; A61K31/4184; A61K47/10; A61K47/22; A61P7/00; A61P35/00; A61P35/02
Foreign References:
| JP2019099557A | 2019-06-24 | |||
| JP2015127300A | 2015-07-09 | |||
| JP2013518130A | 2013-05-20 | |||
| JP2015510940A | 2015-04-13 | |||
| JP2020090481A | 2020-06-11 |
Attorney, Agent or Firm:
TAIYO, NAKAJIMA & KATO (JP)
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