BENZAMIDE DERIVATIVE - CHUGAI PHARMACEUTICAL CO LTD

Title:

BENZAMIDE DERIVATIVE

Document Type and Number:

WIPO Patent Application WO/2005/063689

Kind Code:

A1

Abstract:

A compound which has high angiogenesis inhibitory activity and is useful in therapeutic and preventive drugs which are effective in diseases accompanied by diseased angiogenesis, e.g., cancers and the metastasis of cancers; a process for producing the compound; an intermediate useful in the production; and a medicine or medicinal composition containing the compound. The compound is one represented by the formula (II): a prodrug of the compound, or a pharmaceutically acceptable salt of either.

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Inventors:

KOYANO HIROSHI (JP)
SUDA ATSUSHI (JP)
ASO KOUSUKE (JP)
HADA KIHITO (JP)
ASAI MIYUKI (JP)
HASEGAWA MASAMI (JP)
SATO YASUKO (JP)

Application Number:

PCT/JP2004/019574

Publication Date:

July 14, 2005

Filing Date:

December 27, 2004

Export Citation:

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Assignee:

CHUGAI PHARMACEUTICAL CO LTD (JP)
KOYANO HIROSHI (JP)
SUDA ATSUSHI (JP)
ASO KOUSUKE (JP)
HADA KIHITO (JP)
ASAI MIYUKI (JP)
HASEGAWA MASAMI (JP)
SATO YASUKO (JP)

International Classes:

C07C233/65; C07C233/66; C07C235/46; C07C235/48; C07C235/54; C07C235/64; C07C237/22; C07C237/40; C07C243/38; C07C255/29; C07C255/57; C07C259/10; C07C309/65; C07C323/42; C07C323/62; C07D209/08; C07D213/40; C07D213/56; C07D213/75; C07D215/38; C07D233/54; C07D249/08; C07D277/82; C07D295/155; C07D295/32; C07D307/14; C07D307/52; C07D333/36; (IPC1-7): C07C233/65; C07C233/66; C07C235/46; C07C235/48; C07C235/54; C07C235/64; C07C237/08; C07C237/30; C07C237/40; C07C243/38; C07C255/29; C07C255/57; C07C259/10; C07C323/42; C07C323/62; C07D209/08; C07D215/38; C07D307/14; C07D307/52; C07D319/10; A61K31/167; A61K31/404; A61K31/357; A61P9/00; A61P35/00; A61P43/00

Domestic Patent References:

WO1997003967A1	1997-02-06
WO2002064547A2	2002-08-22
WO2002059080A2	2002-08-01
WO2003103655A1	2003-12-18

Foreign References:

US3755446A

1973-08-28

Other References: