Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
BENZIMIDAZOLE ACETIC ACIDS EXHIBITING CRTH2 RECEPTOR ANTAGONISM AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO2006034418
Kind Code:
A3
Abstract:
The invention relates to benzimidazole acetic acid compounds which function as antagonists of the Chemoattractant Receptor-homologous molecule expressed on T-Helper type 2 cells (CRTH2) receptor. The invention also relates to the use of these compounds to inhibit the binding of prostaglandin D2 and its metabolites or certain thromboxane metabolites to the CRTH2 reeptor and to treat disorders responsive to such inhibition.

Inventors:
BENNANI YOUSSEF L (US)
TUMEY LAWRENCE N (US)
GLEASON ELIZABETH ANN (US)
ROBARGE MICHAEL JOSEPH (US)
Application Number:
PCT/US2005/034028
Publication Date:
May 18, 2006
Filing Date:
September 21, 2005
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
ATHERSYS INC (US)
BENNANI YOUSSEF L (US)
TUMEY LAWRENCE N (US)
GLEASON ELIZABETH ANN (US)
ROBARGE MICHAEL JOSEPH (US)
International Classes:
A61K31/4184; C07D235/06
Foreign References:
US6121308A2000-09-19
Other References:
See also references of EP 1814865A4
Download PDF: