Title:
BENZO OXYGEN-CONTAINING HETEROCYCLIC COMPOUND AND MEDICAL APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/053013
Kind Code:
A1
Abstract:
Disclosed in the present invention are a compound represented by formula Ib or IIb, a cis or trans isomer, enantiomer, diastereomer, racemate, tautomer, solvate, hydrate, and pharmaceutically acceptable salt thereof, or a mixture thereof, a pharmaceutical composition containing the compound, and a use of the compound as a GPR40 agonist, wherein n, E, G1, L1, L2, R1, R2, R3, R4, R5, R5b, R6, R7, X5, X6, X7, Y, Y1, Z, Z1, and the possible isotope substitution label of each element in the compound are as defined in the description.
Inventors:
ZHAN ZHENGYUN (CN)
Application Number:
PCT/CN2021/117623
Publication Date:
March 17, 2022
Filing Date:
September 10, 2021
Export Citation:
Assignee:
AB PHARMA LTD (CN)
International Classes:
C07D407/12; A61K31/19; A61P3/08; A61P3/10; C07D307/00; C07D405/00; C07D407/00
Domestic Patent References:
| WO1999011255A1 | 1999-03-11 | |||
| WO2005087710A1 | 2005-09-22 | |||
| WO2007106469A2 | 2007-09-20 | |||
| WO2004106276A1 | 2004-12-09 | |||
| WO2010143733A1 | 2010-12-16 | |||
| WO2013104257A1 | 2013-07-18 | |||
| WO2015062486A1 | 2015-05-07 |
Foreign References:
| EP1688138A1 | 2006-08-09 | |||
| CN103980235A | 2014-08-13 | |||
| CN101553469A | 2009-10-07 | |||
| US20110313003A1 | 2011-12-22 | |||
| CN1315936A | 2001-10-03 | |||
| CN104507921B | 2017-02-22 | |||
| CN104418801A | 2015-03-18 | |||
| CN103429581B | 2015-08-26 | |||
| CN107001281A | 2017-08-01 | |||
| CN103030646A | 2013-04-10 |
Other References:
"Remington: The Science and Practice of Pharmacy", 2000
See also references of EP 4212528A4
See also references of EP 4212528A4
Attorney, Agent or Firm:
SHANGHAI PATENT & TRADEMARK LAW OFFICE, LLC (CN)
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