Title:
BENZOTHIAZOLESULFONAMIDE DERIVATIVE HAVING TERMINAL CYCLOALKYL GROUP AND MEDICINAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/1996/006088
Kind Code:
A1
Abstract:
A benzothiazolesulfonamide derivative having a terminal cycloalkyl group, represented by general formula (I), or a pharmaceutically acceptable acid-addition salt thereof, (wherein A represents a C2-C6 alkylene group which is unsubstituted or substituted by a C1-C4 alkyl group; B represents either a C1-C6 alkylene group which is unsubstituted or substituted by a C1-C4 alkyl group, or a single bond; R1 represents hydrogen or a C1-C4 alkyl group; R2 and R3 represent each independently hydrogen or a C1-C6 alkyl group, or R2 and R3 are combined together to form a C1-C4 alkyl group which is unsubstituted or substituted by a C1-C4 alkyl group; and R4 represents a C3-C7 cycloalkyl group which is unsubstituted or substituted by a C1-C4 alkyl group). These compounds are useful as the active ingredient of a remedy or preventive for asthma, a bronchodilator, or a medicinal composition for treating or preventing diseases caused by an abnormal IgE antibody level.
Inventors:
TONEGAWA TAKESHI (JP)
NOZAKI YOSHIHIDE (JP)
NOZAKI YOSHIHIDE (JP)
Application Number:
PCT/JP1995/001637
Publication Date:
February 29, 1996
Filing Date:
August 18, 1995
Export Citation:
Assignee:
ASAHI CHEMICAL IND (JP)
TONEGAWA TAKESHI (JP)
NOZAKI YOSHIHIDE (JP)
TONEGAWA TAKESHI (JP)
NOZAKI YOSHIHIDE (JP)
International Classes:
C07D277/64; (IPC1-7): C07D277/64; A61K31/425; A61K31/495
Domestic Patent References:
| WO1992014712A1 | 1992-09-03 | |||
| WO1994019336A1 | 1994-09-01 |
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