Title:
BICYCLIC ANILIDE SPIROHYDANTOIN CGRP RECEPTOR ANTAGONISTS
Document Type and Number:
WIPO Patent Application WO2004082605
Kind Code:
A3
Abstract:
The present invention is directed to compounds of the formula : that are antagonists of CGRP receptors and that are useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Inventors:
BELL IAN M (US)
GALLICCHIO STEVEN N (US)
THEBERGE CORY R (US)
ZHANG XU-FANG (US)
STUMP CRAIG (US)
ZARTMAN C BLAIR (US)
GALLICCHIO STEVEN N (US)
THEBERGE CORY R (US)
ZHANG XU-FANG (US)
STUMP CRAIG (US)
ZARTMAN C BLAIR (US)
Application Number:
PCT/US2004/007289
Publication Date:
November 18, 2004
Filing Date:
March 10, 2004
Export Citation:
Assignee:
MERCK & CO INC (US)
BELL IAN M (US)
GALLICCHIO STEVEN N (US)
THEBERGE CORY R (US)
ZHANG XU-FANG (US)
STUMP CRAIG (US)
ZARTMAN C BLAIR (US)
BELL IAN M (US)
GALLICCHIO STEVEN N (US)
THEBERGE CORY R (US)
ZHANG XU-FANG (US)
STUMP CRAIG (US)
ZARTMAN C BLAIR (US)
International Classes:
C07D233/02; A61K; (IPC1-7): C07D233/02
Foreign References:
| US6548505B1 | 2003-04-15 |
Other References:
See also references of EP 1608627A4
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