BIFUNCTIONAL FUSION PROTEIN AND USE THEREOF

Title:

BIFUNCTIONAL FUSION PROTEIN AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2024/098939

Kind Code:

A1

Abstract:

Provided is a bifunctional fusion protein, comprising a first domain specifically recognizing interleukin-6 receptor (IL-6R), and a second domain specifically binding to cell surface protein CD47. Also provided is a method of using said bifunctional fusion protein to treat or prevent diseases related to IL-6R and/or CD47.

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Inventors:

JIANG YANJING (CN)
WANG WEIHUAN (CN)
ZHOU JINGYUN (CN)
TIAN XINSHENG (CN)
MA RONG (CN)
ZHANG XIAORUI (CN)
LIU XIANGMENG (CN)
ZHANG JUN (CN)
LI ZIQIANG (CN)

Application Number:

PCT/CN2023/117865

Publication Date:

May 16, 2024

Filing Date:

September 08, 2023

Export Citation:

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Assignee:

BEIJING VDJBIO CO LTD (CN)

International Classes:

C07K19/00; A61P35/00; C12N15/62

Attorney, Agent or Firm:

IPSUNNY (CN)

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