Title:
BIODEGRADABLE PEG-BASED POLYMER FORMULATIONS IN OCULAR APPLICATIONS
Document Type and Number:
WIPO Patent Application WO2003086305
Kind Code:
A3
Abstract:
The present invention relates to methods and pharmaceutical compositions involving the use of bioerodible (biodegradable) polymers to address fundamental needs in ocular surgery including sealants and sealing methods, barriers to cellular adhesion and proliferation, and mechanical barriers. In a particular embodiment, the present invention is also directed to the treatment of intraocular hypotony in an eye by limiting the flow of aqueous from the eye. In a preferred embodiment, application of a polymer, such as to the angle of the eye, limits the flow, thereby increasing the intraocular pressure.
Inventors:
SCHWARTZ DANIEL M (US)
DUNCAN KEITH (US)
STEWART JAY (US)
DUNCAN KEITH (US)
STEWART JAY (US)
Application Number:
PCT/US2003/011061
Publication Date:
March 18, 2004
Filing Date:
April 10, 2003
Export Citation:
Assignee:
UNIV CALIFORNIA (US)
SCHWARTZ DANIEL M (US)
DUNCAN KEITH (US)
STEWART JAY (US)
SCHWARTZ DANIEL M (US)
DUNCAN KEITH (US)
STEWART JAY (US)
International Classes:
A61K9/00; A61K31/765; A61K47/10; A61L24/04; (IPC1-7): A61K47/30
Foreign References:
| US6149931A | 2000-11-21 |
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