Title:
BIODEGRADABLE POLYMER SCAFFOLD
Document Type and Number:
WIPO Patent Application WO1999025391
Kind Code:
A3
Abstract:
A polymer scaffold is provided comprising an extensively interconnected macroporous network. The polymer scaffold embodies macropores having a diameter in a range of 0.5-3.5 mm, and preferably in a range of about 1.0 - 2.0 mm. The polymer scaffold is prepared using a novel process which advantageously combines the techniques of particulate leaching and phase inversion to render a process that provides amplified means by which to control the morphology of the resulting polymer scaffold. The polymer scaffold has utility in the area of tissue engineering, particularly as a scaffold for both in vitro and in vivo cell growth.
Inventors:
HOLY CHANTAL E
SHOICHET MOLLY S
DAVIES JOHN E
SHOICHET MOLLY S
DAVIES JOHN E
Application Number:
PCT/CA1998/001052
Publication Date:
August 26, 1999
Filing Date:
November 13, 1998
Export Citation:
Assignee:
BONETEC CORP (CA)
International Classes:
A61F2/00; C12N5/07; A61K35/12; A61K35/32; A61K47/34; A61L27/00; A61L27/14; C08J9/26; C08L67/04; C08L101/12; C08L101/16; C12N5/071; C12N11/08; A61L; (IPC1-7): A61L27/00
Foreign References:
| EP0747068A1 | 1996-12-11 | |||
| US5338772A | 1994-08-16 |
Other References:
MOONEY D J ET AL: "Novel approach to fabricate porous sponges of poly(d,l-lactic-co -glycolic acid) without the use of organic solvents", BIOMATERIALS, vol. 17, no. 14, 1 July 1996 (1996-07-01), pages 1417-1422, XP004032715
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