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Title:
BIOENERGETIC-ACTIVE MATERIAL AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/006113
Kind Code:
A1
Abstract:
Disclosed in the present invention are a bioenergetic-active material and the use thereof. Specifically, disclosed is a bioenergetic-active material, which is a biodegradable polymer. A degradation product of the bioenergetic-active material is a metabolic intermediate product in a tricarboxylic acid cycle and/or a glycolysis pathway, or a polymer monomer which can be converted into a metabolic intermediate product in a tricarboxylic acid cycle and/or a glycolysis pathway, or a polymer monomer which can be converted into an acetyl coenzyme A. The degradation product of the bioenergetic-active material provides the biological energy for tissue cells by means of the tricarboxylic acid metabolic cycle or the glycolysis pathway. The bioenergetic-active material solves the problem that the traditional biodegradable material cannot continuously improve the stability of ATP in cells and the activity of related biomass, and exhibits broad application prospects in the field of bone tissue regeneration, especially in the field of the repair of large segmental bone defects.

Inventors:
LI JIAN (CN)
ZHANG PENG (CN)
Application Number:
PCT/CN2022/109458
Publication Date:
February 02, 2023
Filing Date:
August 01, 2022
Export Citation:
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Assignee:
SHENZHEN INST ADV TECH (CN)
International Classes:
A61L27/18; A61L27/50; A61L27/56
Foreign References:
CN113546213A2021-10-26
CN102936407A2013-02-20
RU2708396C12019-12-06
CN112773940A2021-05-11
CN109676915A2019-04-26
Other References:
FENG JING, SHI QINGSHAN, OUYANG YOUSHENG, CHEN YIBEN: "Research Progress on Biodegradation of Several Polymer Materials", SULIAO KEJI - PLASTICS SCIENCE AND TECHNOLOGY, DALIAN SULIAO YANJIUSUO, DALIAN, CN, vol. 39, no. 2, 28 February 2011 (2011-02-28), CN , pages 94 - 99, XP093028413, ISSN: 1005-3360, DOI: 10.15925/j.cnki.issn1005-3360.2011.02.012
Attorney, Agent or Firm:
BEIJING CHENGHUI LAW FIRM (CN)
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