Title:
BIOLOGICAL MOLECULE DETECTION DEVICE, AND, BIOLOGICAL MOLECULE DETECTION METHOD
Document Type and Number:
WIPO Patent Application WO/2013/176289
Kind Code:
A1
Abstract:
A biological molecule detection device (102FQ) comprising a first biological molecule detection section (82F) having a first electrode (30F) and a second biological molecule detection section (84Q) having a second electrode (30Q), wherein the first electrode (30F) or the second electrode (30Q) is an electrode (32q) having a biological molecule probe-immobilized material (36q) onto which a biological molecule probe (38q) is immobilized. The first electrode (30F) and the second electrode (30Q) provided in the biological molecule detection device (102FQ) are simultaneously brought into contact with an aqueous solution (70) containing at least one biological molecule, and a signal at a solid/liquid interface between the electrodes (30F, 30Q) is detected.
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Inventors:
MIYAHARA YUJI (JP)
GODA TATSURO (JP)
MAEDA YASUHIRO (JP)
GODA TATSURO (JP)
MAEDA YASUHIRO (JP)
Application Number:
PCT/JP2013/064675
Publication Date:
November 28, 2013
Filing Date:
May 27, 2013
Export Citation:
Assignee:
NAT UNIV CORP TOKYO MED & DENT (JP)
International Classes:
C12N15/09; C12M1/00; C12M1/34; C12Q1/68; G01N5/02; G01N21/27; G01N27/414; G01N33/53; G01N33/543
Foreign References:
| US20100248283A1 | 2010-09-30 |
Other References:
REIMHULT, E. ET AL.: "Simultaneous surface plasmon resonance and quartz crystal microbalance with dissipation monitoring measurements of biomolecular adsorption events involving structural transformations and variations in coupled water.", ANAL. CHEM., vol. 76, no. 24, 2004, pages 7211 - 7220
DAMOS, F.S. ET AL.: "Applications of QCM, EIS and SPR in the investigation of surfaces and interfaces for the development of (bio)sensors.", QUIM. NOVA, vol. 27, no. 6, 2004, pages 970 - 979
YUJI MIYAHARA ET AL.: "'Kagaku Sensor no Genjo to Tenbo' Electrical Detection of Bio-molecular Recognition Using Insulated Gate Field Effect Transistors", JOURNAL OF THE SURFACE SCIENCE SOCIETY OF JAPAN, vol. 27, no. 1, 2006, pages 13 - 20
ZONG, Y. ET AL.: "Quartz Crystal Microbalance with Integrated Surface Plasmon Grating Coupler.", ANAL. CHEM., vol. 80, no. 13, 2008, pages 5246 - 5250
GODA, T. ET AL.: "Simultaneous Monitoring of Protein Adsorption Kinetics Using a Quartz Crystal Microbalance and Field-Effect Transistor Integrated Device.", ANAL. CHEM., vol. 84, no. 17, 4 August 2012 (2012-08-04), pages 7308 - 7314
DAMOS, F.S. ET AL.: "Applications of QCM, EIS and SPR in the investigation of surfaces and interfaces for the development of (bio)sensors.", QUIM. NOVA, vol. 27, no. 6, 2004, pages 970 - 979
YUJI MIYAHARA ET AL.: "'Kagaku Sensor no Genjo to Tenbo' Electrical Detection of Bio-molecular Recognition Using Insulated Gate Field Effect Transistors", JOURNAL OF THE SURFACE SCIENCE SOCIETY OF JAPAN, vol. 27, no. 1, 2006, pages 13 - 20
ZONG, Y. ET AL.: "Quartz Crystal Microbalance with Integrated Surface Plasmon Grating Coupler.", ANAL. CHEM., vol. 80, no. 13, 2008, pages 5246 - 5250
GODA, T. ET AL.: "Simultaneous Monitoring of Protein Adsorption Kinetics Using a Quartz Crystal Microbalance and Field-Effect Transistor Integrated Device.", ANAL. CHEM., vol. 84, no. 17, 4 August 2012 (2012-08-04), pages 7308 - 7314
Attorney, Agent or Firm:
NAKAJIMA, Jun et al. (JP)
Nakajima 淳 (JP)
Nakajima 淳 (JP)
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