Title:
BIOMIMETIC OF EVODIA RUTAECARPA FRUIT EXTRACT FOR AMELIORATION OF INFLAMMATION
Document Type and Number:
WIPO Patent Application WO2006023377
Kind Code:
A3
Abstract:
Compositions and methods are provided for reversing and/or inhibiting inflammation, e.g., by inhibiting prostaglandin and/or COX-2 production, using one or more indolequinazoline alkaloids, preferably in combination with butylated hydroxytoluene. The preferred indolequinazoline alkaloids are rutaecarpine, evodiamine, and dehydroevodiamine, which are naturally found in unpurified form in the traditional Chinese medicine Wu Chu Yu made from the fruit of the herb, Evodia rutaecarpa.
Inventors:
YAROSH DANIEL B (US)
BROWN DAVID A (US)
CANNING MATTHEW T (US)
BROWN DAVID A (US)
CANNING MATTHEW T (US)
Application Number:
PCT/US2005/028630
Publication Date:
June 15, 2006
Filing Date:
August 11, 2005
Export Citation:
Assignee:
APPLIED GENETICS INC DERMATICS (US)
YAROSH DANIEL B (US)
BROWN DAVID A (US)
CANNING MATTHEW T (US)
YAROSH DANIEL B (US)
BROWN DAVID A (US)
CANNING MATTHEW T (US)
International Classes:
A61K47/00
Foreign References:
| US5592956A | 1997-01-14 |
Other References:
See also references of EP 1784225A4
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