Title:
BIOPANNING METHODS FOR IDENTIFYING PEPTIDES TARGETING GLIAL PHENOTYPES IN RAMIFIED, PRIMED, AND ACTIVATED BRAIN MICROGLIA AND ASTROCYTES
Document Type and Number:
WIPO Patent Application WO/2024/064728
Kind Code:
A3
Abstract:
Provided herein are biopanning methods for identifying peptides that bind to one or more glial cell subtypes, and peptides identified using the methods described herein. In some embodiments, provided herein are biopanning methods for identifying peptides that bind to glial cell subtypes including surveying glial cells, active glial cells, and/or primed glial cells.
Inventors:
KOSS KYLE (US)
TODD KATHRYN (CA)
DERDA RATMIR (CA)
WERTHEIM JASON (US)
TODD KATHRYN (CA)
DERDA RATMIR (CA)
WERTHEIM JASON (US)
Application Number:
PCT/US2023/074650
Publication Date:
May 16, 2024
Filing Date:
September 20, 2023
Export Citation:
Assignee:
UNIV NORTHWESTERN (US)
UNIV OF ALBERTA (CA)
UNIV OF ALBERTA (CA)
International Classes:
C07K7/06; C12N5/079; C12P21/00; C12Q1/6806; C12Q1/6869; G01N33/48; A61K39/395
Attorney, Agent or Firm:
HULLINGER, Rikki A. (US)
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