Title:
BLADDER CANCER PROGNOSIS DIAGNOSTIC MARKER
Document Type and Number:
WIPO Patent Application WO/2014/027831
Kind Code:
A1
Abstract:
The present invention relates to a novel biomarker for bladder cancer prognosis diagnosis and to a use thereof, and, more specifically, relates to a use thereof in non-muscle invasive (superficial) bladder cancer (NMIBC) diagnosis and bladder cancer prognosis diagnosis by using expression characteristics that accord with the methylation pattern(s) of one or more gene selected from the group consisting of HOXA9, ISL1 and ALDH1A3.
Inventors:
KIM YONG-JUNE (KR)
KIM WUN-JAE (KR)
YOON HYUNG-YOON (KR)
KIM WUN-JAE (KR)
YOON HYUNG-YOON (KR)
Application Number:
PCT/KR2013/007305
Publication Date:
February 20, 2014
Filing Date:
August 14, 2013
Export Citation:
Assignee:
NAT UNIV CHUNGBUK IND ACAD (KR)
KOREA HEALTH INDUSTRY DEV INST KHIDI (KR)
KOREA HEALTH INDUSTRY DEV INST KHIDI (KR)
International Classes:
C12N15/11; C12Q1/68; G01N33/68
Domestic Patent References:
| WO2010123354A2 | 2010-10-28 |
Foreign References:
| JP2004529630A | 2004-09-30 | |||
| US20090023142A1 | 2009-01-22 | |||
| EP2481814A2 | 2012-08-01 |
Other References:
REINERT THOMAS ET AL.: "COMPREHENSIVE GENOME METHYLATION ANALYSIS IN BLADDER CANCER IDENTIFICATION AND VALIDATION OF NOVEL METHYLATED GENES AND APPLICATION OF THESE AS URINARY TUMOR MARKERS", CLINICAL CANCER RESEARCH, vol. 17, no. 17, pages 5582 - 5592
Attorney, Agent or Firm:
WIE, Byoung-Gab (KR)
위병갑 (KR)
위병갑 (KR)
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