Title:
BLOOD-BASED SCREEN FOR DETECTING NEUROLOGICAL DISEASES IN PRIMARY CARE SETTINGS
Document Type and Number:
WIPO Patent Application WO/2015/006489
Kind Code:
A8
Abstract:
The present invention includes methods and kits for the diagnosing a neurological disease within primary care settings comprising: obtaining a blood test sample from a subject, measuring IL-7 and TNFα biomarkers in the blood sample, comparing the level of the one or a combination of biomarkers and neurocognitive screening tests with the level of a corresponding one or combination of biomarkers in a normal blood sample and neurocognitive screening tests, and predicting that an increase in the level of the blood test sample in relation to that of the normal blood sample indicates that the subject is likely to have a neurological disease.
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Inventors:
O'BRYANT SID E (US)
BARBER ROBERT C (US)
XIAO GUANGHUA (US)
GERMAN DWIGHT (US)
BARBER ROBERT C (US)
XIAO GUANGHUA (US)
GERMAN DWIGHT (US)
Application Number:
PCT/US2014/046015
Publication Date:
February 19, 2015
Filing Date:
July 09, 2014
Export Citation:
Assignee:
UNIV NORTH TEXAS (US)
UNIV TEXAS (US)
UNIV TEXAS (US)
International Classes:
G01N33/53; G01N33/573; G01N33/68; G16B20/20; G16B20/40; G16B25/10
Attorney, Agent or Firm:
CHALKER, Daniel J. et al. (LLP14951 North Dallas Parkway, Suite 40, Dallas TX, US)
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