Title:
BLOOD COAGULATION FACTOR XIA INHIBITOR AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/133793
Kind Code:
A1
Abstract:
Provided are a macrocyclic compound having inhibitory blood coagulation factor XIA and/or plasma kallikrein activity, and a pharmaceutical composition thereof. The macrocyclic compound and the pharmaceutical composition thereof can be used for treating or preventing thromboembolic diseases.
Inventors:
ZUO YINGLIN (CN)
WANG JIANCHENG (CN)
LIN JIHUA (CN)
ZHANG YINGXUN (CN)
CAO SHENGTIAN (CN)
WU FANGYUAN (CN)
YANG WEN (CN)
XU JUAN (CN)
WANG XIAOJUN (CN)
ZHANG YINGJUN (CN)
WANG JIANCHENG (CN)
LIN JIHUA (CN)
ZHANG YINGXUN (CN)
CAO SHENGTIAN (CN)
WU FANGYUAN (CN)
YANG WEN (CN)
XU JUAN (CN)
WANG XIAOJUN (CN)
ZHANG YINGJUN (CN)
Application Number:
PCT/CN2018/072988
Publication Date:
July 26, 2018
Filing Date:
January 17, 2018
Export Citation:
Assignee:
SUNSHINE LAKE PHARMA CO LTD (CN)
International Classes:
C07D471/08; A61K31/529; A61P7/00; C07D487/08
Domestic Patent References:
| WO2016053455A1 | 2016-04-07 | |||
| WO2015116882A1 | 2015-08-06 |
Foreign References:
| CN104507924A | 2015-04-08 | |||
| CN105980384A | 2016-09-28 | |||
| CN104520289A | 2015-04-15 | |||
| CN103702999A | 2014-04-02 |
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